The impact of inhalation anesthetics on early postoperative cognitive function and recovery characteristics in Down syndrome patients: a randomized, double – blind study

Table 3 Changes in Patient Alertness, Wellness and Energy during the follow up for the two study groups (Desflurane group: DES-group and Sevoflurane group: SEVO-group)

	Group	Baseline	90′ after recovery	4 h after recovery	P1-value Baseline vs 90′	P2-value Baseline vs 4 h	P3-value 90′ vs 4 h
Patient Alertness	DES	2.91 (0.29)	2.82 (0.39)	2.91 (0.29)	1.000	1.000	1.000
Patient Alertness	SEVO	2.62 (0.5)	2.1 (0.54)	2.43 (0.51)	<0.001*	0.220	0.019*
Patient Wellness	DES	2.73 (0.46)	2.32 (0.65)	2.73 (0.55)	0.080	1.000	0.084
Patient Wellness	SEVO	2.29 (0.78)	1.38 (0.59)	2.05 (0.74)	<0.001*	0.375	<0.001*
Patient Energy	DES	2.82 (0.39)	2.64 (0.49)	2.86 (0.35)	0.329	1.000	0.200
Patient Energy	SEVO	2.86 (0.36)	2 (0.45)	2.57 (0.51)	<0.001*	0.049*	<0.001*

All comparisons were made using logarithmic transformations; Data are presented as mean (SD); * indicates statistical significance (P < 0.05); P₁: p-value for group effect; P₂: p-value for time effect; P₃: Effects reported include differences between the groups in the degree of change (repeated measurements ANOVA)

ISSN: 1471-2253