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Table 2 Changes in PCFT during the follow up for the two study groups (Desflurane group: DES-group and Sevoflurane group: SEVO-group)

From: The impact of inhalation anesthetics on early postoperative cognitive function and recovery characteristics in Down syndrome patients: a randomized, double – blind study

 

Group

Baseline

90′ after recovery

4 h after recovery

P2

Baseline vs

90′

P2

Baseline vs

4 h

P2

90′ vs

4 h

P3

PCFT total scores

DES

137 (54.6)

125.6 (52.5)

133.4 (53.1)

<0.001*

0.163

<0.001*

<0.001*

SEVO

111.57 (55.47)

78.76 (52.41)

94 (53.97)

<0.001*

<0.001*

<0.001*

P1

0.138

0.006*

0.021*

 

Orientation

DES

11.7 (4.9)

10.5 (4.9)

11.6 (5)

0.033*

1.000*

<0.001*

0.073

SEVO

8.96 (3.82)

6.67 (3.25)

7.95 (3.2)

<0.001*

0.018*

<0.001*

P1

0.054

0.004*

0.006*

    

Recall

DES

10.3 (5.4)

10 (5.5)

10.4 (5.3)

1.000

1.000

0.986

0.033*

SEVO

10.67 (4.62)

7.52 (4.09)

9.14 (3.88)

<0.001*

0.017*

<0.001*

P1

0.799

0.102

0.397

 

Language

DES

59.5 (20)

54.6 (20.7)

58.6 (20.9)

0.005*

1.000

0.003*

0.001*

SEVO

48.19 (23.53)

35.14 (26.27)

41.19 (25.1)

<0.001*

<0.001*

<0.001*

P1

0.098

0.010*

0.018*

 

Praxis

Group

Baseline

90′ after recovery

4 h after recovery

P2

Baseline vs

90′

P2

Baseline vs

4 h

P2

90′ vs

4 h

P3

DES

41.1 (18.9)

36.9 (16.6)

39.9 (17.9)

0.016*

0.521

0.012*

<0.001*

SEVO

34.19 (21.8)

22.48 (17.53)

27.62 (19.14)

<0.001*

<0.001*

<0.001*

 

P1

0.273

0.008*

0.036*

    

Calculation

DES

14.4 (12.7)

12.4 (10.7)

12.9 (10.6)

0.034*

0.056

0.656

0.646

SEVO

9.19 (7.48)

6.95 (6.05)

8.1 (6.46)

0.021*

0.263

0.043*

 

P1

0.110

0.049*

0.082

    
  1. PCFT Prudhoe Cognitive Function Test. Data are presented as mean (SD); * indicates statistical significance (P < 0.05); P1: P-value for group effect; P2: P-value for time effect; P3: Effects reported include differences between the groups in the degree of change (repeated measurements ANOVA)