Skip to main content

Table 3 Pulmonal parameters. Data shown as mean values and standard deviation

From: Influence of rosuvastatin treatment on cerebral inflammation and nitro-oxidative stress in experimental lung injury in pigs

  

VO

OAI

SA

SBA

PEEP

BLH

4 ± 0

4 ± 0

4 ± 0

4 ± 0

(cm H2O)

0 h

4 ± 0

6 ± 2

5 ± 2

5 ± 2

 

6 h

4 ± 0

9 ± 2*

10 ± 2*

10 ± 2*

 

12 h

4 ± 0

7 ± 3*

8 ± 1*

9 ± 2*

 

18 h

4 ± 0

7 ± 3

7 ± 2

9 ± 3*

Ppeak

BLH

15 ± 2

16 ± 3

16 ± 2

15 ± 1

(cm H2O)

0 h

14 ± 1

28 ± 6*

25 ± 5*

25 ± 4*

 

6 h

15 ± 2

28 ± 3*

28 ± 4*

27 ± 3*

 

12 h

16 ± 2

28 ± 6*

27 ± 4*

26 ± 2*

 

18 h

17 ± 2

30 ± 5*

26 ± 5*

25 ± 5*

VT

BLH

6 ± 0

6 ± 1

6 ± 0

6 ± 0

(ml/kg)

0 h

6 ± 0

7 ± 1

6 ± 0

6 ± 0

 

6 h

6 ± 0

7 ± 1

6 ± 0

6 ± 0

 

12 h

6 ± 0

6 ± 0

6 ± 0

6 ± 0

 

18 h

6 ± 0

6 ± 0

6 ± 0

6 ± 0

etCO2

BLH

39 ± 3

38 ± 4

42 ± 2

42 ± 1

(mmHg)

0 h

36 ± 2

37 ± 4

39 ± 3

38 ± 2

 

6 h

37 ± 4

39 ± 3

41 ± 2

41 ± 3

 

12 h

37 ± 2

39 ± 3

39 ± 2

40 ± 3

 

18 h

36 ± 2

39 ± 4

38 ± 2

40 ± 4

FiO2

BLH

40 ± 0

40 ± 0

40 ± 0

40 ± 0

(%)

0 h

100 ± 0

100 ± 0

100 ± 0

100 ± 0

 

6 h

40 ± 0

55 ± 10*

59 ± 9*

65 ± 9*

 

12 h

39 ± 4

48 ± 10

51 ± 13

59 ± 12*

 

18 h

40 ± 0

45 ± 10

41 ± 3

54 ± 17

EVLWI

BLH

11 ± 1

10 ± 2

13 ± 3

14 ± 3

(ml/kg)

0 h

12 ± 1

19 ± 4*

20 ± 4*

26 ± 8*#±

 

6 h

12 ± 2

21 ± 7*

21 ± 5*

25 ± 3*

 

12 h

14 ± 2

17 ± 6

21 ± 6*

24 ± 3*#

 

18 h

14 ± 3

17 ± 5

19 ± 4

23 ± 5*#±

paO2/FiO2

BLH

503 ± 65

496 ± 58

467 ± 63

449 ± 91

(mmHg)

0 h

544 ± 66

101 ± 28*

86 ± 34*

72 ± 20*

 

6 h

452 ± 55

188 ± 70*

166 ± 40*

159 ± 53*

 

12 h

453 ± 73

221 ± 48*

158 ± 45*

153 ± 53*

 

18 h

400 ± 59

216 ± 50*

205 ± 43*

207 ± 105*

Wet-to-dry

 

5 ± 0

6 ± 1

6 ± 1

6 ± 1

Ratio

     
  1. *p < 0.05 vs VO; # p < 0.05 vs OAI; + p < 0.05 vs SA
  2. Abbreviations: blh, baseline; etCO2, end tidal CO2; EVLWI, extravascular lung water index; FiO2, inspiratory fraction of O2; OAI, lung injury by central venous injection of oleic acid; PEEP, positive end expiratory pressure; Ppeak, peak pressure; SA, statin treatment after lung injury; SBA, statin treatment 12 h before and directly after lung injury; VO, ventilation only; Vt, tidal volume
Back to article page

BMC Anesthesiology

ISSN: 1471-2253

Contact us