Table 2 Demographics and outcomes
From: Circulatory trajectories after out-of-hospital cardiac arrest: a prospective cohort study
Patient characteristics and outcomes | All | Comatose | Awake |
|---|---|---|---|
N = 50 | n = 42 (84%) | n = 8 (16%) | |
Demographics | |||
Age, years, mean (sd) | 62.7 (15.3) | 64.8 (14.5) | 51.8 (14.5) |
Male sex, no. (%) | 40 (80) | 35 (83) | 5 (62) |
Body mass index, mean (sd) | 27.5 (6.6) | 27.7 (7) | 26.4 (2.3) |
Medical history | |||
Charlson comorbidity index, median (Q1–Q3) | 3 (2–4) | 3 (2–5) | 2 (1–3) |
Cerebral performance category, median (Q1–Q3) | 1 (1–1) | 1 (1–1) | 1 (1–1) |
Cardiac arrest | |||
Location, no. (%) | |||
Place of residence | 19 (38) | 16 (38) | 3 (37) |
Public place | 21 (42) | 16 (38) | 5 (63) |
Other | 10 (20) | 10 (24) | 0 (0) |
Bystander witnessed, no. (%) | 42 (84) | 34 (80) | 8 (100) |
Bystander performed CPR, no. (%) | 44 (88) | 37 (88) | 7 (87) |
First monitored rhythm, no. (%) | |||
Shockable | |||
Ventricular fibrillation | 37 (74) | 30 (71) | 7 (88) |
Ventricular tachycardia | 2 (4) | 1 (2) | 1 (12) |
Nonshockable | |||
Asystole | 4 (8) | 4 (10) | 0 (0) |
Pulseless electric activity | 7 (14) | 7 (17) | 0 (0) |
Number of defibrillations, median (Q1–Q3) | 2 (1–4) | 2 (1–4) | 1 (1–2) |
Time from cardiac arrest to event, median (Q1–Q3) | |||
Start of basic life support—min | 1 (1–2) | 1 (1–2) | 1 (1–2) |
Start of advanced life support—min | 9 (5–13) | 10 (5–15) | 5 (2–7) |
Return of spontaneous circulation—min | 24 (14–32) | 26 (19–35) | 8 (4–14) |
Adrenaline—mg, median (Q1–Q3) | 0 (0–2) | 1 (0–3) | 0 (0–0) |
Presumed etiology, no. (%) | |||
Cardiac | 42 (84) | 34 (81) | 8 (100) |
Asphyxia | 5 (10) | 5 (12) | 0 (0) |
Other | 3 (6) | 3 (7) | 0 (0) |
Certain pulmonary aspiration, no. (%) | 9 (18) | 9 (21) | 0 (0) |
At admission | |||
Body temperature, °C, mean (sd) | 35.3 (1.1) | 35.2 (1.0) | 36.5 (0.6) |
In circulatory shocka, no. (%) | 18 (36) | 18 (42) | 0 (0) |
Arterial blood gas, mean (sd) | |||
pH | 7.18 (0.14) | 7.17 (0.15) | 7.28 (0.05) |
pCO2, kPa | 6.2 (1.8) | 6.4 (1.9) | 5.2 (0.7) |
Base excess, mmol/l | -9.4 (7.4) | -9.7 (7.7) | -7.6 (5.2) |
HCO3, mmol/l | 17.9 (4.5) | 17.7 (4.4) | 19.1 (4.7) |
Lactate, mmol/l | 6.7 (4.2) | 6.9 (4.5) | 5.9 (2.7) |
Oxygen saturation, % | 92.1 (9.4) | 91.5 (10.1) | 95.2 (3.1) |
Acute intervention, no. (%) | |||
Angiography | 26 (52) | 21 (50) | 5 (63) |
Percutaneous coronary intervention | 21 (42) | 17 (40) | 4 (50) |
Computer tomography scan | 18 (36) | 16 (38) | 2 (25) |
Pulmonary artery catheter | 30 (60) | 30 (71) | 0 (0) |
Therapeutic hypothermia protocol initiated | 28 (56) | 28 (67) | 0 (0) |
Prone position, no. (%) | 2 (4) | 2 (5) | 0 (0) |
Simplified Acute Physiology Score II b, mean (sd) | 62 (19) | 68 (12) | 28 (9) |
Length of stay | |||
ICU, days, median (Q1–Q3) | 6 (3–12) | 8 (4–12) | 2 (2–3) |
Ventilator time, hours, median (Q1–Q3) | 64 (12–162) | 93 (28–173) | 0 (0–0) |
Hospital, days, median (Q1–Q3) | 14 (7–20) | 14,5 (7–20) | 13 (6–16) |
Outcome, 180 days | |||
Mortality, n (%) | 16 (32) | 16 (38) | 0 (0) |
Cerebral | 10 (20) | 10 (23) | - |
Circulatory | 2 (4) | 2 (5) | - |
Respiratory | 0 (0) | 0 (0) | - |
Multiorgan failure c | 3 (6) | 3 (7) | - |
Other/unknown | 1 (2) | 1 (2) | - |
Cerebral performance category, n (%) | |||
I—Normal | 22 (44) | 22 (52) | 8 (100) |
II—Moderate disability | 2 (4) | 2 (5) | 0 (0) |
III—Severe disability | 2 (4) | 2 (5) | 0 (0) |
IV—Coma or vegetative state | 0 (0) | 0 (0) | 0 (0) |
V—Brain death | 16 (32) | 16 (38) | 0 (0) |