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Fig. 5 | BMC Anesthesiology

Fig. 5

From: The expression of kappa-opioid receptor promotes the migration of breast cancer cells in vitro

Fig. 5

The effects of PI3K/AKT signaling on migration and related protein expressions of breast cancer cells with OPRK1 knockdown. A MDA-MB-231 cells transfected with OPRK1 siRNA were treated with Recilisib or Buparlisib for 24 h, and the migration was performed by wound healing analysis, representative images (left) and statistical analysis (right) are shown. B MDA-MB-231 cells transfected with OPRK1 siRNA were treated with Recilisib or Buparlisib for 24 h, and the protein expressions of E-cadherin, MMP2, N-cadherin, Snail and Vimentin were determined by western blot. GAPDH was used as loading control

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