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Fig. 3 | BMC Anesthesiology

Fig. 3

From: Sevoflurane blocks glioma malignant development by upregulating circRELN through circRELN-mediated miR-1290/RORA axis

Fig. 3

MiR-1290 was a target of circRELN. A The potential target miRNAs were predicted by circinteractome and circbank. B The efficiency of circRELN overexpression was checked by qPCR. C and D The expression of predicted target miRNAs in T98G and LN18 cells was checked by qPCR. E The binding site between circRELN and miR-1290 was shown. F The efficiency of miR-1290 mimic was checked by qPCR. G and H The binding relationship between circRELN and miR-1290 was verified by dual-luciferase reporter assay. I and J The binding relationship between circRELN and miR-1290 was verified by RIP assay. K The expression of miR-1290 in tissue samples was detected by qPCR. L The expression of miR-1290 in cell lines was detected by qPCR. (M) The expression of miR-1290 in Sev-treated T98G and LN18 cells was detected by qPCR. *P < 0.05

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BMC Anesthesiology

ISSN: 1471-2253

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