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Table 1 Comparison of EC50 and EC90 values of pipecuronium, vecuronium, and rocuronium

From: Carboxymethyl-γ-cyclodextrin, a novel selective relaxant binding agent for the reversal of neuromuscular block induced by aminosteroid neuromuscular blockers: an ex vivo laboratory study

NMBA

EC50 (μM)

EC90 (μM)

Pipecuronium

1.38 (1.33–1.42)

1.68 (1.58–1.79)

Pipecuronium + CMGCD

2.04 (1.94–2.16)

2.90 (2.58–3.25)

Vecuronium

3.69 (3.59–3.80)

5.29 (4.97–5.63)

Rocuronium

7.50 (6.93–8.12)

11.36 (9.64–13.39)

  1. Values are given as mean and 95% confidence interval. EC50, effective concentration for 50% effect; EC90, effective concentration for 90% effect; Pipecuronium + CMGCD, pipecuronium effective concentrations after a priming dose of 13.3 μM carboxymethyl-γ-cyclodextrin. CMGCD Carboxymethyl-γ-cyclodextrin
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BMC Anesthesiology

ISSN: 1471-2253

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