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Fig. 3 | BMC Anesthesiology

Fig. 3

From: Carboxymethyl-γ-cyclodextrin, a novel selective relaxant binding agent for the reversal of neuromuscular block induced by aminosteroid neuromuscular blockers: an ex vivo laboratory study

Fig. 3

Concentration–response curves for different NMBAs.A Concentration–response curves for pipecuronium, vecuronium, and rocuronium. Normalized contraction force amplitude as a function of NMBA concentration on a logarithmic scale (logarithm to base 10/ log10). The curve is the best fit curve calculated from measurements on n = 5 different specimens by non-linear regression. Measurement points represent mean values of normalized contraction force amplitude at a given concentration. Error bars show the standard deviation of measurement points. B Shift in the concentration–response curve of pipecuronium after a priming dose of 13.3 μM CMGCD. CMGCD: carboxymethyl-γ-cyclodextrin; NMBA: neuromuscular blocking agent

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BMC Anesthesiology

ISSN: 1471-2253

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