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Fig. 3 | BMC Anesthesiology

Fig. 3

From: Protective effects of dexmedetomidine on cerebral ischemia/reperfusion injury via the microRNA-214/ROCK1/NF-κB axis

Fig. 3

DEX attenuates CIRI in rats with MCAO by increasing miR-214 expression. A Neurological deficit scores for rats injected with miR-214 inhibitor. B miR-214 expression in rat brain tissues detected by RT-qPCR. C Infarction area of rats injected with miR-214 inhibitor observed by TTC staining. D Damage of neurons in hippocampal regions determined by HE staining. E Apoptosis rate of neurons in hippocampal regions examined by TUNEL staining. For panel A, B, C, and E, comparisons were made using unpaired t test. * p < 0.05 compared with rats injected with NC inhibitor

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BMC Anesthesiology

ISSN: 1471-2253

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