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Table 4 Postoperative total fentanyl consumption during the first 24 h

From: Effects of lidocaine, dexmedetomidine, and their combination infusion on postoperative nausea and vomiting following laparoscopic hysterectomy: a randomized controlled trial

Total fentanyl consumption (µg)

Group C (n = 60)

Group L (n = 60)

Group D (n = 60)

Group LD (n = 60)

P-value

aP

bP

cP

Postoperative 2 h

45.5 ± 16.9

40.5 ± 12.4

36.5 ± 5.5*

36.3 ± 4.2*

 < 0.001

0.331

0.001

0.001

Postoperative 6 h

125.4 ± 17.4

117.1 ± 13.4*

112.2 ± 11.7*

110.0 ± 7.1*✩

 < 0.001

0.024

 < 0.001

 < 0.001

Postoperative 12 h

230.9 ± 22.0

222.0 ± 18.0

217.5 ± 15.0*

214.4 ± 10.2*✩

 < 0.001

0.099

0.001

 < 0.001

Postoperative 24 h

439.6 ± 29.1

429.9 ± 22.9

423.3 ± 20.4*

420.2 ± 16.5*

 < 0.001

0.242

0.004

 < 0.001

  1. Data are present as mean ± standard deviation
  2. Group C Control group, Group L Lidocaine group, Group D Dexmedetomidine group, Group LD Lidocaine combined with dexmedetomidine group
  3. *P versus Group C, ✩P versus Group L
  4. aP for group C vs group L, bP for group C vs group D, cP for group C vs group LD