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Table 1 Patient characteristics, stratified by hemodynamic instability status

From: Dexmedetomidine-induced hemodynamic instability in patients undergoing orthopedic upper limb surgery under brachial plexus block: a retrospective study

 

Stable group

(n = 99)

Unstable group

(n = 17)

P value

Age (years)

54.0 (36.0–62.0)

59.0 (48.0–68.0)

0.057

Female [n (%)]

39 (39.4)

13 (76.5)

0.010*

Body weight (kg)

65.6 (12.6)

63.2 (10.0)

0.449

BMI (kg/m2)

24.3 (3.6)

26.1 (4.0)

0.058

Classification by BMI

 Underweight [n (%)]

5 (5.1)

0

0.008

 Normal weight [n (%)]

52 (52.5)

5 (29.4)

 

 Overweight [n (%)]

38 (38.4)

8 (47.1)

 

 Obesity [n (%)]

4 (4.0)

4 (23.5)

 

Underlying disease [n (%)]

 Hypertension

20 (20.2)

8 (47.1)

0.037*

 History of CAD

4 (4.0)

1 (5.9)

0.764

 Diabetes mellitus

12 (12.1)

3 (17.6)

0.813

Preoperative laboratory test

 AST (IU/L)

23.0 (20.0–28.0)

25.0 (20.5–34.0)

0.296

 ALT (IU/L)

22.0 (18.0–29.0)

21.0 (19.0–38.0)

0.550

 Albumin (g/dL)

4.6 (4.3–4.7)

4.4 (4.3–4.6)

0.094

Surgery time (min)

37.0 (25.0–56.0)

30.0 (25.0–53.5)

0.734

PACU stay (min)

62.0 (53.0–74.0)

57.0 (50.0–93.0)

0.896

Hospital stay (days)

6.0 (4.0–8.0)

6.0 (5.0–9.5)

0.195

Time to hemodynamic instability after initiating DMED administration (min)

N/A

67.0 (37.4–96.6)

N/A

  1. Continuous variables are presented as mean (SD) or median (interquartile range). Categorical variables are presented as number (%)
  2. Underweight < 18.5 kg/m2; normal weight 18.5–24.9 kg/m2; overweight 25.0–29.9 kg/m2; obesity \(\ge\) 30.0 kg/m2
  3. BMI body mass index, CAD coronary artery disease, AST aspartate aminotransferase, ALT alanine animotransferase, PACU postanesthesia care unit, DMED dexmedetomidine, N/A not applicable
  4. *P < 0.05 by chi-square test
  5. P < 0.05 by Mann–Whitney rank-sum test