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Table 2 Primary Outcomes

From: Intraoperative protective ventilation in patients undergoing major neurosurgical interventions: a randomized clinical trial

 

Control treatment

LPV strategy

P value

Patients with one or more adverse events, n (%)

 Composite

8 (26.7)

8 (26.7)

0.999

 Hypoxemic events

6 (20.0)

2 (6.7)

0.129

 Haemoglobin desaturation

0 (0.0)

0 (0.0)

0.999

 Hypotension or bradycardia

2 (6.7)

6 (20.0)

0.129

Cerebral tension by the surgeon (only in case of brain surgery)

 Grade 1 n (%)

7 (33.3)

7 (30.4)

0.677

 Grade 2 n (%)

9 (42.9)

10 (43.5)

 Grade 3 n (%)

5 (23.8)

6 (26.1)

 Grade 4 n (%)

0 (0.0)

0 (0.0)

PaCO2 control

 Patients with one or more episode of hypercapnia n (%)

1 (3.3)

2 (6.6)

0.554

 Overall PaCO2 recorded (mmHg), mean (SD)

35.5 (4.0)

37.1 (3.4)

0.002