Dexmedetomidine post-conditioning attenuates cerebral ischemia following asphyxia cardiac arrest through down-regulation of apoptosis and neuroinflammation in rats

Table 1 The change of MAP and HR after CA/CPR^a,b

Minutes after CA/CPR(min)	MAP(mmHg)			p-value	HR(beats/min)			p-value
Minutes after CA/CPR(min)	Sham (n = 6)	Control (n = 12)	Dex (n = 12)	p-value	Sham (n = 6)	Control (n = 12)	Dex (n = 12)	p-value
0	125.17 ± 2.79	180.92 ± 4.74	162.42 ± 5.45	< 0.0001	416.50 ± 3.83	386.67 ± 2.10	371.00 ± 1.35	< 0.0001
5	125.17 ± 2.79	145.92 ± 3.32	124.08 ± 2.57	< 0.0001	415.00 ± 4.15	397.08 ± 1.83	380.75 ± 1.42	< 0.0001
10	125.17 ± 2.79	135.42 ± 2.68	112.50 ± 1.78	< 0.0001	412.83 ± 4.22	371.92 ± 1.51	360.08 ± 1.73	< 0.0001
15	125.17 ± 1.94	116.33 ± 1.50	91.42 ± 4.58	< 0.0001	415.33 ± 3.83	348.67 ± 3.20	323.58 ± 3.73	< 0.0001
20	124.67 ± 1.51	106.17 ± 1.53	85.25 ± 3.19	< 0.0001	415.00 ± 2.45	329.33 ± 2.77	295.75 ± 1.66	< 0.0001
25	125.67 ± 1.97	100.75 ± 1.42	78.00 ± 1.13	< 0.0001	413.83 ± 2.40	300.00 ± 2.30	285.75 ± 2.22	< 0.0001
30	125.50 ± 2.59	102.75 ± 1.14	82.00 ± 0.95	< 0.0001	414.67 ± 1.97	300.08 ± 2.15	280.25 ± 1.60	< 0.0001
35	125.50 ± 1.38	105.08 ± 0.79	80.42 ± 1.00	< 0.0001	415.33 ± 2.73	312.42 ± 1.78	277.33 ± 1.61	< 0.0001
40	124.67 ± 2.73	107.33 ± 1.50	84.58 ± 4.54	< 0.0001	415.00 ± 3.69	346.50 ± 5.66	309.75 ± 1.71	< 0.0001
45	125.67 ± 1.51	108.25 ± 0.97	84.67 ± 4.60	< 0.0001	415.50 ± 3.94	361.25 ± 10.04	345.00 ± 3.16	< 0.0001
50	125.67 ± 2.42	111.08 ± 1.83	94.67 ± 6.10	< 0.0001	415.50 ± 4.46	383.92 ± 2.39	359.25 ± 8.02	< 0.0001
55	126.17 ± 2.79	114.50 ± 1.45	100.00 ± 3.30	< 0.0001	414.67 ± 4.03	407.42 ± 1.83	385.00 ± 2.89	< 0.0001
60	125.83 ± 1.94	120.08 ± 2.02	105.58 ± 1.08	< 0.0001	415.33 ± 4.08	417.17 ± 5.62	396.42 ± 3.58	< 0.0001

^a Data are mean ± SD
^b p-value<0.05
Table 1Changes in the mean arterial pressures (MAP) and heart rate (HR) in the Control and Dex groups after CA/CPR (n = 6–12)

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