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Table 1 Patients’ characteristics

From: Early recognition of cardiac surgery-associated acute kidney injury: lack of added value of TIMP2 IGFBP7 over short-term changes in creatinine (an observational pilot study)

 

CS-AKI

n=27 (42 %) patients

No CS-AKI

n=38 (58 %) patients

p

Age (years)

78 [75-86]

79 [75-86]

0.14

Female gender (n [%])

12 (44 %)

21 (55 %)

0.39

Body mass index (kg/m2)

27 [25-30]

26 [23-27]

0.04

Weight (kg)

75 [67-83]

69 [59-79]

0.06

EuroSCORE II (%)

3.4 [2.0-5.5]

1.8 [1.4-3.5]

0.016

SAPS II

27 [24-32]

24 [22-27]

0.006

Comorbidities

 Hypertension (n [%])

17 (63 %)

28 (76 %)

0.27

 Diabetes mellitus (n [%])

5 (19 %)

9 (23 %)

0.58

 COPD (n [%])

2 (7 %)

1 (3 %)

0.38

 History of heart surgery (n [%])

1 (4 %)

1 (3 %)

0.82

 Preoperative LV ejection fraction <35 % (n [%])

1 (4 %)

0 (0 %)

0.24

 History of peripheral vascular surgery (n [%])

3 (11 %)

2 (5 %)

0.40

 Preoperative serum creatinine (μmol/L)

82 [74-91]

79 [66-92]

0.34

 Preoperative eGFR (mL/minute/1.73 m2)

75 [54-83]

70 [64-81]

0.85

 eGFR before CPB <60 mL/min/1.73 m2

7 (26 %)

5 (13 %)

0.38

Cross-clamp time (minutes)

45 [38-58]

56 [43-68]

0.014

CPB time (minutes)

61 [53-76]

68 [56-89]

0.09

CPB priming (mL)

1000 [1000-1100]

1000 [1000-1025]

0.79

Volume expansion (mL)

 Intraoperative

850 [500-1100]

600 [500-1000]

0.33

 Post-operative (24h)

750 [500-1250]

500 [250-875]

0.046

Intraoperative transfusion

 Red blood cell autotransfusion (mL)

400 [210-500]

400 [300-500]

0.85

 Packed red blood cell (n patients)

6 (22 %)

13 (35 %)

0.35

 Packed red blood cell >2 packs (n patients)

1 (4 %)

0 (0 %)

0.24

 Fresh frozen plasma (n patients)

1 (4 %)

0 (0 %)

0.24

 Platelet transfusion (n patients)

1 (3 %)

1 (4 %)

0.82

Postoperative (48h) transfusion

 Packed red blood cell (n patients)

6 (22 %)

4 (11 %)

0.22

 Packed red blood cell > 2 packs (n patients)

1 (4%)

0 (0 %)

0.24

 Fresh frozen plasma (n patients)

1 (4 %)

1 (3 %)

0.82

 Platelet transfusion (n patients)

1 (4 %)

0 (0 %)

0.24

Post-operative (24 h) urine output (mL/kg/h)

0.7 [0.5-0.9]

1.0 [0.7-1.3]

0.003

Diuretics within 24 postoperative hours (n [%])

19 (70 %)

14 (38 %)

0.010

Vancomycin for antibioprophylaxis (n [%])

0 (0 %)

0 (0 %)

-

Aminoglycosides within 48 postop. hours (n [%])

0 (0 %)

1 (3 %)

0.39

Re-operation within 48 hours

2 (7 %)

0 (0 %)

0.10

ICU length of stay (days)

3 [2-5]

2 [1-3]

0.037

Hospital length of stay after the surgery (days)

10 [8-14]

9 [8-13]

0.37

Hospital mortality (n [%])

0 (0 %)

1 (3 %)

0.39

  1. eGFR estimated glomerular filtration rate (modification of diet in renal disease equation), COPD Chronic obstructive pulmonary disease, ICU intensive care unit, SAPS II simplified acute physiology score 2, LV left ventricle, CPB cardiopulmonary bypass
  2. Results are expressed as n (%) or median [interquartile range]
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BMC Anesthesiology

ISSN: 1471-2253

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