Table 1 Baseline data for the survival and death groups of cancer patients with sepsis
Total (n = 233) | Survival (n = 190) | death (n = 43) | P | |
|---|---|---|---|---|
Sex, male | 169(72.5 %) | 139(73.2 %) | 30(69.8 %) | 0.65 |
Age(year) | 63.7 ± 9.9 | 63.5 ± 9.9 | 64.9 ± 10.1 | 0.4 |
Infection category | ||||
Respiratory | 79(33.9 %) | 66(34.7 %) | 13(30.2 %) | 0.21 |
Gastrointestinal | 17(7.3 %) | 11(7.9 %) | 4(9.3 %) | 0.32 |
Abdominal cavity | 99(42.3 %) | 80(42.1 %) | 18(41.9 %) | 0.54 |
Thoracic cavity | 27(11.6 %) | 23(12.1 %) | 7(16.2 %) | 0.14 |
Catheter related blood stream infection | 3(1.3 %) | 3(1.6 %) | 0 | 0.13 |
Genitourinary | 5(2.1 %) | 5(2.1 %) | 0 | 0.21 |
Others | 3(1.3 %) | 2(1.1 %) | 1(2.3 %) | 0.16 |
Septic shock | 94(40.3 %) | 60(31.6 %) | 34(79.1 %) | 0.001 |
AKI | 40(17.2 %) | 14(7.4 %) | 26(60.5 %) | 0.001 |
ARF | 123(52.3 %) | 88(46.3 %) | 35(81.4 %) | 0.001 |
SIMD a | 42/126 (33.3 %) | 30/98(30.6 %) | 12/28(42.9) | 0.26 |
Total MV time(day) | 3.6 ± 5.9 | 2.7 ± 4.7 | 7.5 ± 8.7 | 0.001 |
ICU stay time(day) | 7.8 ± 5.9 | 7.7 ± 5.3 | 8.6 ± 7.7 | 0.46 |
Fluid-balance(ml/kg) | ||||
24 hr | 49.4 ± 35.8 | 46.1 ± 33.1 | 53.9 ± 43.3 | 0.083 |
72 hr | 63.1 ± 54.9 | 50.5 ± 45.8 | 118.5 ± 58.2 | 0.002 |
Emergency surgery | 62(26.7 %) | 51(26.8 %) | 11(25.6 %) | 0.26 |
Lactate(mmol/l) | 2.9 ± 2.2 | 2.6 ± 1.6 | 4.6 ± 3.5 | 0.001 |
Leucocyte (10^9/l) | 13.3 ± 8.3 | 13.2 ± 8.4 | 13.7 ± 8.3 | 0.73 |
PCT (ng/ml) | 17.6 ± 45.2 | 15.7 ± 43.6 | 25.4 ± 51.5 | 0.21 |
Cardiac biomarkers | ||||
BNP (pg/ml) | ||||
d1 | 673.6 ± 786.6 | 618.1 ± 724.7 | 919.0 ± 989.6 | 0.01 |
d3 | 656.6 ± 912.4 | 370.2 ± 456.9 | 1922.1 ± 1284.1 | 0.000 |
cTnI(ng/ml) | ||||
d1 | 0.04(0.02/0.17) | 0.03(0.01/0.16) | 0.08(0.03/0.23) | 0.04 |
d3 | 0.03(0.01/0.12) | 0.02(0.01/0.05) | 0.21(0.11/1.11) | 0.02 |
SOFA Score | 5(4/10) | 4(3/7) | 9(4/12) | 0.000 |