Table 1 Recommended dose of sugammadex by reliable sources

Manufacturer’s instructions [1]

4 mg/kg is recommended if spontaneous recovery of the twitch response has reached 1–2 PTCs and there are no twitch responses to TOF stimulation.

2 mg/kg is recommended if spontaneous recovery has reached the reappearance of the second twitch in response to TOF stimulation.

Miller’s anesthesia textbook [2]

Three different doses of sugammadex are recommended according to the level of block. A large dose (16 mg/kg) is given during intense block (no response to PTC stimulation), a medium dose (4 mg/kg) during deep block (two or more responses to PTC), and a low dose (2 mg/kg) during moderate block (two or more responses to TOF stimulation).

Review article [3]

For reversal of moderate block (TOF count, 1–3), a dose of 2 mg/kg is recommended; for reversal of deep block (PTC ≥ 1), a dose of 4 mg/kg is recommended.

Online resource [4]

Deep block (at least 1–2 post-tetanic counts and prior to the second twitch following TOF stimulation): 4 mg/kg as a single dose. Moderate block (after appearance of the second twitch following TOF stimulation): 2 mg/kg as a single dose.