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Table 2 Emergence profile during awake and in the postanesthetic care unit

From: Dexmedetomidine decreased the post‐thyroidectomy bleeding by reducing cough and emergence agitation – a randomized, double‐blind, controlled study

  Group D (n = 69) Group S (n = 70) P-value
Extubation time (min) 10.0 [8.0] 8.0 [5.25] 0.728
Recovery time (min) 41.0 [16.0] 42.0 [13.0] 0.604
Cough reflex (grade 0/1/2/3) 21/29/13/6 12/20/22/16 0.015
Incidence of severe cough (grade 3) 6 (4.3) 16 (11.5) 0.022
 Odds ratio (95% CI) 0.321 (0.118, 0.879) Referent  
 Relative risk (95% CI) 0.635 (0.460, 0.876) 1.974 (0.978, 3.987)  
 Risk difference (95% CI) Referent 1.339 (1.277, 1.401)  
RSS at PACU 2.3 (0.7) 1.7 (1.4) 0.002
Classified RSS    0.01
 Agitated (RSS 1) 11 (7.9) 28 (20.1)  
 Calm (RSS 2–3) 50 (36.0) 41 (29.5)  
 Sedated (RSS 4–7) 8 (5.8) 1 (0.7)  
Agitated RSS (RSS 1) 11 (7.9) 28 (20.1)  
 Odds ratio (95% CI) 0.284 (0.127, 0.635) Referent  
 Relative risk (95% CI) 0.585. (0.432, 0.792) 2.056 (1.213, 3.486)  
 Risk difference (95% CI) Referent 1.471 (1.409, 1.533)  
Desaturation 0 (0) 0 (0)
  1. Values are the mean (standard deviation), median [interquartile range], or number (%). Group D, administered dexmedetomidine (0.6 μg/kg/hr); Group S, administered normal saline as a control. Extubation time, the time interval from discontinuing the desflurane to extubate; recovery time, time interval from discontinuing the desflurane to transferred to the ward
  2. CI confidence interval, RSS Ramsay Sedation Scale, PACU postanesthetic care unit. Patients were classified as agitated, RSS 1; Calm, RSS 2–3; Sedated, RSS 4–6