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Table 1 Demographic and clinical data at the 2nd interim analysis

From: Bilateral posterior Quadratus Lumborum block for pain relief after cesarean delivery: a randomized controlled trial

Data

IT morphine (n = 20)

IT morphine with QLB (n = 18)

QLB (n = 20)

p-value

Age (yr)

32.25 ± 5.26

31.06 ± 6.58

32.70 ± 6.70

0.705

Body mass index (kg/m2)

27.90 ± 2.98

28.92 ± 4.05

28.17 ± 4.15

0.694

Operation

   

0.806

 C/S

16 (80.0%)

13 (72.2%)

16 (80.0%)

 

 C/S with TS

4 (20.0%)

5 (27.8%)

4 (20.0%)

 

Operative time (min)

57.75 ± 16.18

60.28 ± 17.94

68.50 ± 15.82

0.113

Total morphine in 24 h (mg)

5.5 (0–25)

5.0 (0–36)

17.5 (1–40)

< 0.001

Pruritus

   

0.007

 0

9 (45.0%)

15 (83.3%)

20 (100%)

 

 1

8 (40.0%)

2 (11.1%)

0 (0.0%)

 

 2

2 (10.0%)

1 (5.6%)

0 (0.0%)

 

 3

1 (5.0%)

0 (0.0%)

0 (0.0%)

 

PONV

   

0.380

 0

19 (95.0%)

18 (100%)

20 (100%)

 

 1

1 (5.0%)

0 (0.0%)

0 (0.0%)

 
  1. Data presented as mean ± standard deviation, number and percentage, or median and range (min, max). A p-value< 0.05 indicates statistical significance.
  2. Abbreviations: IT intrathecal, QLB quadratus lumborum block, C/S cesarean section, TS tubal sterilization, PONV postoperative nausea and vomiting
  3. Group QLB had significantly higher morphine consumption in 24 h than both IT (p = 0.003) and IT + QLB (p = 0.002). There was no significant difference in morphine consumption between IT and IT + QLB (p = 1.000).
  4. Group IT had a significantly higher number of patients with pruritus than both IT + QLB (p = 0.020) and QLB (p < 0.001). There was no significant difference in pruritus between IT + QLB and QLB (p = 0.480).