Variables | Group | T1 | T2 | T3 | T4 | Mean diff [95% CI], P1 | Mean diff [95% CI], P2 | Mean diff [95% CI], P3 |
---|---|---|---|---|---|---|---|---|
PaO2 (mmHg) | VCV | 296 ± 30 | 291 ± 30 | 269 ± 17 | 266 ± 24 | −5.6 [−19.2 to 7.9], 0.9539 | −27.7 [−41.3 to − 14.2], < 0.0001 | −30.5 [− 44.1 to − 17.0], < 0.0001 |
PCV-VG | 296 ± 27 | 297 ± 32 | 270 ± 17 | 268 ± 20 | 1.1 [− 12.3 to 14.5], > 0.9999 | − 26.2 [− 39.5 to − 12.8], < 0.0001 | −28.6 [− 41.9 to − 15.2], < 0.0001 | |
Mean diff [95% CI] | 0.5 [− 14.2 to 15.2] | −6.2 [− 20.9 to 8.5] | − 1.1 [− 15.8 to 13.6] | −1.4 [− 16.1 to 13.3] | ||||
P | > 0.9999 | > 0.9999 | > 0.9999 | > 0.9999 | “ | |||
PaCO2 (mmHg) | VCV | 37.8 ± 1.1 | 39.8 ± 2.5 | 42.3 ± 2.5 | 43.1 ± 3.2 | 1.9 [0.6 to 3.3], 0.0016 | 4.4 [3.1 to 5.8], < 0.0001 | 5.3 [3.9 to 6.6], < 0.0001 |
PCV-VG | 37.9 ± 1.0 | 40.0 ± 2.8 | 41.3 ± 2.6 | 42.6 ± 3.0 | 2.1 [0.8 to 3.4], 0.0006 | 3.4 [2.1 to 4.7], < 0.0001 | 4.7 [3.4 to 6.1], < 0.0001 | |
Mean diff [95% CI] | −0.0 [−1.5 to 1.4] | − 0.2 [−1.6 to 1.3] | 1.0 [− 0.4 to 2.5] | 0.5 [− 0.9 to 1.9] | ||||
P | > 0.9999 | > 0.9999 | 0.2841 | > 0.9999 | ||||
OI | VCV | 99 ± 20 | 69 ± 11 | 64 ± 10 | 62 ± 10 | −39.7 [−50.5 to −29.9], < 0.0001 | −46.5 [− 56.2 to − 36.7], < 0.0001 | − 49.6 [− 59.4 to − 39.9], < 0.0001 |
PCV-VG | 95 ± 17 | 71 ± 13 | 65 ± 11 | 64 ± 11 | −32.2 [− 41.8 to − 22.6], < 0.0001 | −40.4 [− 50.1 to − 30.8], < 0.0001 | −41.6 [− 51.2 to − 31.9], < 0.0001 | |
Mean diff [95% CI] | 5.0 [−5.5 to 15.4] | − 2.5 [− 12.9 to 7.9] | −1.1 [− 11.5 to 9.4] | − 3.1 [− 13.5 to 7.4] | ||||
P | 0.9286 | > 0.9999 | > 0.9999 | > 0.9999 | ||||
Vd/VT (%) | VCV | 37.1 ± 2.9 | 39.6 ± 4.1 | 42.0 ± 3.7 | 42.3 ± 3.4 | 2.7 [0.7 to 4.7], 0.0036 | 4.8 [2.9 to 6.8], < 0.0001 | 5.3 [3.3 to 7.3], < 0.0001 |
PCV-VG | 37.1 ± 2.7 | 39.3 ± 4.5 | 40.9 ± 3.1 | 42.1 ± 3.9 | 2.2 [0.2 to 4.1], 0.0265 | 3.8 [1.8 to 5.7], < 0.0001 | 4.9 [2.9 to 6.9], < 0.0001 | |
Mean diff [95% CI] | −0.0 [−2.1 to 2.1] | 0.5 [− 1.5 to 2.6] | 1.1 [− 1.0 to 3.1] | 0.3 [− 1.7 to 2.4] | ||||
P | > 0.9999 | > 0.9999 | 0.8145 | > 0.9999 |