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Table 2 Intra−/postoperative variables

From: Impact of goal-directed hemodynamic management on the incidence of acute kidney injury in patients undergoing partial nephrectomy: a pilot randomized controlled trial

 

Intervention group (n = 72)

Control group (n = 72)

P value

Airway management

  

>  0.999

 Endotracheal tube

59 (81.9%)

59 (81.9%)

 

 Laryngeal mask

13 (18.1%)

13 (18.1%)

 

Intraoperative anesthetics

 Use of midazolam

18 (25%)

21 (29.2%)

0.574

 Use of etomidate

30 (41.7%)

35 (48.6%)

0.402

 Use of cisatracurium

50 (69.4%)

47 (65.3%)

0.594

 Propofol (mg)

537 (393, 686)

510 (365, 650)

0.562

 Sufentanil (μg)

30 (20, 38)

25 (20, 39)

0.689

 Remifentanil (μg)

560 (0, 837)

562 (30, 815)

0.781

 Rocuronium (mg)

50 (40, 50)

50 (40, 50)

0.998

Vasoactive drugs

 Use of dobutamine

65 (90.3%)

0 (0.0%)

< 0.001

 Use of norepinephrine

6 (8.3%)

0 (0.0%)

0.028

 Use of ephedrine

28 (38.9%)

23 (31.9%)

0.384

Use of diuretics during surgery

54 (75.0%)

56 (77.8%)

0.695

 Mannitol (g)

25 (25, 25) (n = 39)

25 (25, 25) (n = 37)

0.201

 Furosemide (mg)

10 (10, 10) (n = 49)

10 (10, 10) (n = 52)

0.215

Dexamethasone (mg)

5 (5, 5)

5 (5, 5)

0.229

Fluids infusion (ml)a

1650 (1525, 2100)

1600 (1213, 1800)

0.012

Urine output (ml)

400 (200, 600)

300 (200, 488)

0.020

Estimated blood loss (ml)

50 (30, 100)

50 (23, 100)

0.885

Packed red blood cells

1 (1.4%)

1 (1.4%)

>  0.999

Duration of anesthesia (min)

131 ± 42

135 ± 49

0.649

Type of surgery

  

>  0.999

 Laparoscopic

64 (88.9%)

64 (88.9%)

 

 Open-abdominal

8 (11.1%)

8 (11.1%)

 

Surgical position

  

>  0.999

 Supine

3 (4.2%)

3 (4.2%)

 

 Lateral

69 (95.8%)

69 (95.8%)

 

Duration of clamping (min) (n = 71)b

22 ± 8

22 ± 6

0.848

Before clampingb

 Mean BIS

50 ± 7

51 ± 7

0.348

 Mean CI (L/min/m2)

2.7 (2.3, 3.1)

–

–

 Mean SVV (%)

6 (5, 8)

–

–

 Mean SBP (mmHg)

121 ± 15

120 ± 16

0.833

 Mean MAP (mmHg)

88 ± 10

86 ± 9

0.181

 Mean HR (beats per minute)

62 ± 8

60 ± 9

0.362

After reperfusionb

 Mean BIS

53 ± 8

51 ± 7

0.134

 Mean CI (L/min/m2)

3.3 (3, 3.5) ‡

–

–

 Mean SVV (%)

5 (4, 6) ‡

–

–

 Mean SBP (mmHg)

136 ± 9

120 ± 15

< 0.001

 Mean MAP (mmHg)

100 ± 4

86 ± 10

< 0.001

 Mean HR (beats per minute)

70 ± 10

63 ± 8

< 0.001

Duration of surgery (min)

93 ± 38

96 ± 45

0.629

Use of diuretics within 3 day after surgeryc

2 (2.8%)

1 (1.4%)

0.560

  1. Data are mean ± SD, number (%), or median (interquartile range)
  2. SBP systolic blood pressure, MAP mean arterial pressure, HR heart rate, BIS bispectral index, CI cardiac index, SVV stroke volume variation
  3. aOnly crystalloid fluid was allowed except blood transfusion
  4. bOne patient in the intervention group did not undergo renal artery clamping; one in the control group converted to radical nephrectomy without renal artery clamping
  5. ‡ P < 0.001 compared with value before clamping within the intervention group (analyzed with Wilcoxon signed-rank test)
  6. cIncluding torasemide and furosemide