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Table 3 Comparison of VAS at different time points in the four groups (n = 30, \( \overline{x}\pm s \))

From: Effects of dexmedetomidine on intraoperative hemodynamics, recovery profile and postoperative pain in patients undergoing laparoscopic cholecystectomy: a randomized controlled trial

  

NS group

D1 group

D2 group

D3 group

P-value

VAS

t1

4.0 ± 1.4

3.3 ± 1.5

3.1 ± 1.2*

3.2 ± 1.0*

0.039

t2

4.7 ± 1.3

4.7 ± 1.6

3.5 ± 1.5*#

3.6 ± 1.2*#

0.000

t3

4.5 ± 1.3

4.2 ± 1.1

3.4 ± 1.5*#

3.5 ± 1.1*#

0.002

t4

4.3 ± 1.5

3.8 ± 1.0

3.1 ± 1.6*#

3.0 ± 1.1*#

0.000

t5

3.3 ± 1.2

3.2 ± 0.8

2.4 ± 1.3*#

2.4 ± 0.9*#

0.000

t6

2.5 ± 0.8

2.3 ± 0.8

1.7 ± 0.8*#

1.7 ± 0.7*#

0.000

  1. Data presented as mean ± SD
  2. VAS Visual Analogue Scale, t1 20min after operation, t2 2h after operation, t3 6h after operation, t4 12h after operation, t5 24h after operation, t6 48h after operation
  3. *p < 0.05 vs. NS group; # p < 0.05 vs. D1 group