Table 2 Baseline characteristics
Characteristic | Intention-to-treat analysis | Per-protocol analysis | ||||
|---|---|---|---|---|---|---|
TA (n = 75) | SC (n = 75) | P | TA (n = 72) | SC (n = 71) | P | |
Sex, male, n (%) | 42 (56.00) | 38 (50.67) | 0.513 | 40 (55.56) | 34 (47.89) | 0.359 |
Age (yrs), mean ± SD | 63.75 ± 13.75 | 63.35 ± 14.89 | 0.860 | 63.99 ± 13.75 | 63.54 ± 15.20 | 0.876 |
BMI (kg/m2), mean ± SD | 24.69 ± 4.63 | 23.68 ± 4.43 | 0.173 | 24.70 ± 4.68 | 23.67 ± 4.53 | 0.181 |
ASA classification, n (%) | 0.479 | 0.676 | ||||
III | 21 (28.00) | 25 (33.33) | 21 (29.17) | 23 (32.39) | ||
IV | 54 (72.00) | 50 (66.67) | 51 (70.83) | 48 (67.61) | ||
Preoperative bleeding risk, n (%) | 32 (42.67) | 40 (53.33) | 0.191 | 31 (43.06) | 38 (53.52) | 0.210 |
Anesthesia time (min), mean ± SD | 356.27 ± 92.01 | 383.4 ± 117.22 | 0.135 | 355.90 ± 93.70 | 385.35 ± 119.65 | 0.110 |
Operations, n (%) | 0.484 | 0.345 | ||||
Valve surgery | 33 (44.00) | 39 (52.00) | 31 (43.06) | 38 (53.52) | ||
CABG | 35 (46.67) | 26 (34.67) | 34 (47.22) | 23 (32.39) | ||
CABG + Valve surgery | 4 (5.33) | 6 (8.00) | 4 (5.56) | 6 (8.45) | ||
Other | 3 (4.00) | 4 (5.33) | 3 (4.17) | 4 (5.63) | ||
On CPB, n (%) | 58 (77.33) | 58 (77.33) | > 0.999 | 55 (76.39) | 56 (78.87) | 0.722 |
Heparin dose (mg), mean ± SD | 219.47 ± 94.13 | 220.61 ± 106.27 | 0.660 | 218.33 ± 95.42 | 221.56 ± 106.56 | 0.570 |
Protamine dose (mg), mean ± SD | 287.93 ± 132.98 | 293.53 ± 151.72 | 0.613 | 286.25 ± 135.17 | 294.72 ± 153.47 | 0.530 |
No. of catheters, n (%) | 0.050 | 0.024* | ||||
Single catheter | 30 (40.00) | 42 (56.00) | 28 (38.89) | 41 (57.75) | ||
Double catheters | 45 (60.00) | 33 (44.00) | 44 (61.11) | 30 (42.25) | ||
Insertion attempts, n (%) | 0.827 | 0.373 | ||||
> 2 Attempts | 13 (17.33) | 12 (16.00) | 13 (18.06) | 9 (12.68) | ||
1–2 Attempts | 62 (82.67) | 63 (84.00) | 59 (81.94) | 62 (87.32) | ||
Insertion technique, n (%) | 0.618 | 0.453 | ||||
Landmark technique | 29 (38.67) | 32 (42.67) | 27 (37.50) | 31 (43.66) | ||
Ultrasonography-guided technique | 46 (61.33) | 43 (57.33) | 45 (62.50) | 40 (56.34) | ||
Intraoperative LPRC transfusion, n (%) | 42 (56.00) | 53 (70.67) | 0.062 | 40 (55.56) | 51 (71.83) | 0.043* |
Intraoperative FFP transfusion, n (%) | 51 (68.00) | 57 (76.00) | 0.275 | 48 (66.67) | 56 (78.87) | 0.101 |
Intraoperative LPPC transfusion, n (%) | 52 (69.33) | 58 (77.33) | 0.268 | 49 (68.06) | 56 (78.87) | 0.143 |
Intraoperative cryoprecipitate transfusion, n (%) | 9 (12.00) | 15 (20.00) | 0.181 | 8 (11.11) | 15 (21.13) | 0.103 |
Intraoperative autologous blood transfusion, n (%) | 55 (73.33) | 56 (74.67) | 0.852 | 54 (75.00) | 54 (76.06) | 0.883 |
Postoperative bleeding risk, n (%) | 72 (96) | 74 (98.67) | 0.620 | 69 (95.83) | 70 (98.59) | 0.620 |