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Table 4 Pharmacokinetic variables: plasma concentrations (ng/ml) of chloroprocaine and CABA. Mean ± SD is shown; BLQL: below the quantification limit (4.0 ng/ml)

From: Spinal anaesthesia with Chloroprocaine HCl 1% for elective lower limb procedures of short duration: a prospective, randomised, observer-blind study in adult patients

  FAS
Dose Group Chloroprocaine 1% CABA
30 mg 40 mg 50 mg 30 mg 40 mg 50 mg
Pre-dose (0) BLQL BLQL BLQL BLQL BLQL BLQL
5′ post-dose BLQL BLQL BLQL 16.13 ± 20.11 20.41 ± 23.04 24.89 ± 20.34
10′ post-dose BLQL BLQL BLQL 41.44 ± 31.78 38.85 ± 25.49 75. 83 ± 67.64
30′ post-dose BLQL BLQL BLQL 57.46 ± 43.77 67.18 ± 36.90 97.65 ± 61.70
60′ post-dose BLQL BLQL BLQL 47.02 ± 41.38 53.09 ± 31.80 78.38 ± 48.40