Table 2 Time to onset/offset variables. Data are expressed as mean ± SD. Tsb: time to onset of sensory block, Tmb: time to onset of motor block, Trs: time to readiness for surgery, Tsbmax: time to maximum level of sensory block, Trd: time to regression of two dermatomes; TS1: time to regression of sensory block to S1, Tea time to regression of both motor and sensory blocks; Trmb: time to regression of motor block; Tua: time to unassisted ambulation; Tra: time to first administration of rescue analgesia; Tuv: time to first spontaneous urinary voiding; Thd: time to home discharge

Dose Group

Group 30 mg

Group 40 mg

Group 50 mg

p value

Tsb (min)

5.4 ± 3.0

6.6 ± 3.4

4.8 ± 2.0

NS

Tmb (min)

6.3 ± 3.2

6.0 ± 3.3

4.4 ± 2.3

NS

Trs (min)

8.0 ± 4.1

7.9 ± 4.7

5.3 ± 2.0

30 vs 50 mg p = 0.0259

Tsbmax (h)

0.22 ± 0.14

0.24 ± 0.1

0.23 ± 0.10

NS

Trd (h)

0.687 ± 0.361

0.851 ± 0.468

0.695 ± 0.290

NS

TS1 (h),

Tea (h)

1.761 ± 0.348

2.127 ± 0.457

2.195 ± 0.386

30 vs 50 mg p = 0.0094

30 vs 40 mg p = 0.0344

Trmb (h)

1.438 ± 0.409

1.480 ± 0.400

1.661 ± 0.459

NS

Tua (h)

2.662 ± 0.789

3.361 ± 1.120

3.213 ± 0.856

30 vs 40 mg p = 0.0471

Tra (h)

0.717 ± 0.397

0.315 ± 0.049

–

NS

Tuv

2.530 ± 0.761

3.361 ± 1.120

3.067 ± 0.755

30 vs 50 mg p = 0.0412

30 vs 40 mg p = 0.0171

Thd

3.021 ± 1.012

3.545 ± 1.281

3.530 ± 0.887

NS