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Table 2 Time to onset/offset variables. Data are expressed as mean ± SD. Tsb: time to onset of sensory block, Tmb: time to onset of motor block, Trs: time to readiness for surgery, Tsbmax: time to maximum level of sensory block, Trd: time to regression of two dermatomes; TS1: time to regression of sensory block to S1, Tea time to regression of both motor and sensory blocks; Trmb: time to regression of motor block; Tua: time to unassisted ambulation; Tra: time to first administration of rescue analgesia; Tuv: time to first spontaneous urinary voiding; Thd: time to home discharge

From: Spinal anaesthesia with Chloroprocaine HCl 1% for elective lower limb procedures of short duration: a prospective, randomised, observer-blind study in adult patients

  FAS
Dose Group Chloroprocaine 1%
Group 30 mg Group 40 mg Group 50 mg p value
Tsb (min) 5.4 ± 3.0 6.6 ± 3.4 4.8 ± 2.0 NS
Tmb (min) 6.3 ± 3.2 6.0 ± 3.3 4.4 ± 2.3 NS
Trs (min) 8.0 ± 4.1 7.9 ± 4.7 5.3 ± 2.0 30 vs 50 mg p = 0.0259
Tsbmax (h) 0.22 ± 0.14 0.24 ± 0.1 0.23 ± 0.10 NS
Trd (h) 0.687 ± 0.361 0.851 ± 0.468 0.695 ± 0.290 NS
TS1 (h),
Tea (h)
1.761 ± 0.348 2.127 ± 0.457 2.195 ± 0.386 30 vs 50 mg p = 0.0094
30 vs 40 mg p = 0.0344
Trmb (h) 1.438 ± 0.409 1.480 ± 0.400 1.661 ± 0.459 NS
Tua (h) 2.662 ± 0.789 3.361 ± 1.120 3.213 ± 0.856 30 vs 40 mg p = 0.0471
Tra (h) 0.717 ± 0.397 0.315 ± 0.049 NS
Tuv 2.530 ± 0.761 3.361 ± 1.120 3.067 ± 0.755 30 vs 50 mg p = 0.0412
30 vs 40 mg p = 0.0171
Thd 3.021 ± 1.012 3.545 ± 1.281 3.530 ± 0.887 NS