From: Muscle weakness, functional capacities and recovery for COVID-19 ICU survivors
Characteristics | All patients N = 23 | Limbs weakness N = 16 | No Limbs weakness N = 7 | P-Value |
---|---|---|---|---|
Gender F/M, n | 6/17 | 3/13 | 3/4 | 0.31 |
Age | 64.6 ± 9.6 | 65.8 ± 11 | 62.4 ± 8 | 0.47 |
Weight (Kg) | 85.2 ± 12.3 | 86.2 ± 13.2 | 82.9 ± 10.5 | 0.25 |
Body Mass Index (Kg/m2) | 29.1 ± 3.5 | 28.9 ± 3.3 | 29.4 ± 4.4 | 0.74 |
SAPS II at ICU admission | 39.7 ± 14.9 | 38.1 ± 15.6 | 43.3 ± 13.5 | 0.45 |
Co-morbidity | ||||
Chronic Pulmonary Disease, n (%) | 9 (39) | 6 (37) | 3 (43) | 1 |
Chronic Cardiac Insufficiency, n (%) | 6 (23) | 5 (31) | 1 (14) | 0.11 |
Obesity, n (%) | 9 (39) | 6 (37) | 3 (43) | 0.49 |
Chronic Kidney Disease, n (%) | 0 (0) | 0 (0) | 0 (0) | – |
Diabetes mellitus, n (%) | 8 (35) | 4 (25) | 4 (57) | 0.18 |
Hypertension, n (%) | 11 (48) | 7 (44) | 4 (57) | 0.66 |
Between admission and awakening | ||||
Septic shock, n (%) | 13 (56) | 11 (69) | 2 (46) | 0.16 |
Use of catecholamines, n (%) | 16 (69) | 14 (87) | 2 (46) | 0.01 |
No. of days of neuromuscular blockers | 4.9 ± 3.8 | 5.6 ± 4 | 3 ± 2.3 | 0.11 |
No. of days on prone position | 1 (2) | 3.2 ± 2.8 | 0.8 ± 1.6 | 0.04 |
Use of corticosteroid, n (%) | 2 (12) | 1 (6) | 1 (14) | 0.5 |
Ventilator use (days) | 15.3 ± 10.3 | 18.5 ± 10.4 | 8.2 ± 5.5 | 0.02 |
AC mode ventilation use | 8.9 ± 6.2 | 10.7 ± 6.3 | 4.8 ± 3.6 | 0.03 |
PS mode ventilation use | 5.8 ± 4.4 | 6.9 ± 4.7 | 3.4 ± 2.4 | 0.08 |
No of physiotherapy sessions during MV | 9 ± 8.3 | 12 ± 8.2 | 3 ± 4.3 | 0.01 |
ICU length of stay | 22.2 ± 12.3 | 25.9 ± 12.3 | 13.6 ± 7.1 | 0.02 |
Muscle and physical function | ||||
MRC score | 41 ± 14 | 34 ± 11.2 | 56.6 ± 3.8 | < 0.001 |
MIP value | 40 ± 11 | 37.7 ± 11.8 | 46.1 ± 6.3 | 0.11 |
Peak expiratory cough flow | 94.2 ± 34.8 | 95.4 ± 39.7 | 91 ± 18.5 | 0.79 |
ICU mobility scale at ICU discharge | 5.4 ± 2.1 | 4.3 ± 1.5 | 8 ± 0.6 | < 0.001 |
Walk less than 100 m at 1 month | 7 (31) | 7 (44) | 0 (0) | 0.06 |
Rehabilitation access after ICU | 10 (43) | 9 (56) | 1 (14) | 0.08 |