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Table 1 Patients characteristics

From: Muscle weakness, functional capacities and recovery for COVID-19 ICU survivors

Characteristics

All patients N = 23

Limbs weakness N = 16

No Limbs weakness N = 7

P-Value

Gender F/M, n

6/17

3/13

3/4

0.31

Age

64.6 ± 9.6

65.8 ± 11

62.4 ± 8

0.47

Weight (Kg)

85.2 ± 12.3

86.2 ± 13.2

82.9 ± 10.5

0.25

Body Mass Index (Kg/m2)

29.1 ± 3.5

28.9 ± 3.3

29.4 ± 4.4

0.74

SAPS II at ICU admission

39.7 ± 14.9

38.1 ± 15.6

43.3 ± 13.5

0.45

Co-morbidity

 Chronic Pulmonary Disease, n (%)

9 (39)

6 (37)

3 (43)

1

 Chronic Cardiac Insufficiency, n (%)

6 (23)

5 (31)

1 (14)

0.11

 Obesity, n (%)

9 (39)

6 (37)

3 (43)

0.49

 Chronic Kidney Disease, n (%)

0 (0)

0 (0)

0 (0)

 Diabetes mellitus, n (%)

8 (35)

4 (25)

4 (57)

0.18

 Hypertension, n (%)

11 (48)

7 (44)

4 (57)

0.66

Between admission and awakening

 Septic shock, n (%)

13 (56)

11 (69)

2 (46)

0.16

 Use of catecholamines, n (%)

16 (69)

14 (87)

2 (46)

0.01

 No. of days of neuromuscular blockers

4.9 ± 3.8

5.6 ± 4

3 ± 2.3

0.11

 No. of days on prone position

1 (2)

3.2 ± 2.8

0.8 ± 1.6

0.04

 Use of corticosteroid, n (%)

2 (12)

1 (6)

1 (14)

0.5

 Ventilator use (days)

15.3 ± 10.3

18.5 ± 10.4

8.2 ± 5.5

0.02

 AC mode ventilation use

8.9 ± 6.2

10.7 ± 6.3

4.8 ± 3.6

0.03

 PS mode ventilation use

5.8 ± 4.4

6.9 ± 4.7

3.4 ± 2.4

0.08

 No of physiotherapy sessions during MV

9 ± 8.3

12 ± 8.2

3 ± 4.3

0.01

 ICU length of stay

22.2 ± 12.3

25.9 ± 12.3

13.6 ± 7.1

0.02

Muscle and physical function

 MRC score

41 ± 14

34 ± 11.2

56.6 ± 3.8

< 0.001

 MIP value

40 ± 11

37.7 ± 11.8

46.1 ± 6.3

0.11

 Peak expiratory cough flow

94.2 ± 34.8

95.4 ± 39.7

91 ± 18.5

0.79

 ICU mobility scale at ICU discharge

5.4 ± 2.1

4.3 ± 1.5

8 ± 0.6

< 0.001

 Walk less than 100 m at 1 month

7 (31)

7 (44)

0 (0)

0.06

 Rehabilitation access after ICU

10 (43)

9 (56)

1 (14)

0.08

  1. Variables are expressed in mean ± SD or n with percentage. Abbreviations: SAPS Simplified Acute Physiology Score, ICU Intensive Care Unit, No Number, AC Assit-Controlled, PS Pressure Support, MRC Medical Research Council, MIP Maximal Inspiratory Pressure