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Table 1 Patients characteristics

From: Muscle weakness, functional capacities and recovery for COVID-19 ICU survivors

Characteristics All patients N = 23 Limbs weakness N = 16 No Limbs weakness N = 7 P-Value
Gender F/M, n 6/17 3/13 3/4 0.31
Age 64.6 ± 9.6 65.8 ± 11 62.4 ± 8 0.47
Weight (Kg) 85.2 ± 12.3 86.2 ± 13.2 82.9 ± 10.5 0.25
Body Mass Index (Kg/m2) 29.1 ± 3.5 28.9 ± 3.3 29.4 ± 4.4 0.74
SAPS II at ICU admission 39.7 ± 14.9 38.1 ± 15.6 43.3 ± 13.5 0.45
Co-morbidity
 Chronic Pulmonary Disease, n (%) 9 (39) 6 (37) 3 (43) 1
 Chronic Cardiac Insufficiency, n (%) 6 (23) 5 (31) 1 (14) 0.11
 Obesity, n (%) 9 (39) 6 (37) 3 (43) 0.49
 Chronic Kidney Disease, n (%) 0 (0) 0 (0) 0 (0)
 Diabetes mellitus, n (%) 8 (35) 4 (25) 4 (57) 0.18
 Hypertension, n (%) 11 (48) 7 (44) 4 (57) 0.66
Between admission and awakening
 Septic shock, n (%) 13 (56) 11 (69) 2 (46) 0.16
 Use of catecholamines, n (%) 16 (69) 14 (87) 2 (46) 0.01
 No. of days of neuromuscular blockers 4.9 ± 3.8 5.6 ± 4 3 ± 2.3 0.11
 No. of days on prone position 1 (2) 3.2 ± 2.8 0.8 ± 1.6 0.04
 Use of corticosteroid, n (%) 2 (12) 1 (6) 1 (14) 0.5
 Ventilator use (days) 15.3 ± 10.3 18.5 ± 10.4 8.2 ± 5.5 0.02
 AC mode ventilation use 8.9 ± 6.2 10.7 ± 6.3 4.8 ± 3.6 0.03
 PS mode ventilation use 5.8 ± 4.4 6.9 ± 4.7 3.4 ± 2.4 0.08
 No of physiotherapy sessions during MV 9 ± 8.3 12 ± 8.2 3 ± 4.3 0.01
 ICU length of stay 22.2 ± 12.3 25.9 ± 12.3 13.6 ± 7.1 0.02
Muscle and physical function
 MRC score 41 ± 14 34 ± 11.2 56.6 ± 3.8 < 0.001
 MIP value 40 ± 11 37.7 ± 11.8 46.1 ± 6.3 0.11
 Peak expiratory cough flow 94.2 ± 34.8 95.4 ± 39.7 91 ± 18.5 0.79
 ICU mobility scale at ICU discharge 5.4 ± 2.1 4.3 ± 1.5 8 ± 0.6 < 0.001
 Walk less than 100 m at 1 month 7 (31) 7 (44) 0 (0) 0.06
 Rehabilitation access after ICU 10 (43) 9 (56) 1 (14) 0.08
  1. Variables are expressed in mean ± SD or n with percentage. Abbreviations: SAPS Simplified Acute Physiology Score, ICU Intensive Care Unit, No Number, AC Assit-Controlled, PS Pressure Support, MRC Medical Research Council, MIP Maximal Inspiratory Pressure