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Table 2 Intraoperative fentanyl consumption and ANI score

From: Comparative study of analgesia nociception index (ANI) vs. standard pharmacokinetic pattern for guiding intraoperative fentanyl administration among mastectomy patients

Variable

ANI-guided group (n = 30)

Control group (n = 30)

Mean difference (95% CI)

P-value

Total intraoperative fentanyl consumption

 Total dose (μg)

158.3 ± 38.5

162.5 ± 40.9

−4.2 (−24.7 to 16.4)

0.686

 Average dose (μg·kg−1·h−1)

1.01 ± 0.33

1.16 ± 0.34

−0.14 (− 0.31 to 0.03)

0.105

Mean ANI score

65.2 ± 17.7

63.0 ± 18.2

2.2 (0.3 to 4.0)

0.022

  1. Data are expressed as mean ± SD; Unpaired Student’s t-test
  2. ANI Analgesia Nociception Index