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Table 1 Baseline demographic and clinical characteristics in the studied population group

From: Persistently higher serum sCD40L levels are associated with outcome in septic patients

  Healty control
n = 6
SS
n = 19
SWS
n = 49
P
Sex (male/female) 3/3 12/7 34/15 0.586
Age (years)-median (p25-p75) 53.00 (42.25–62.00) 76.00 (71.00–81.00) 61.00 (45.00–73.00) 0.005
sCD40L(pg/ml)-median (p25-p75) 469.50 (406.83–547.36) 831.36 (526.58–981.72) 1022.68 (554.85–2215.13) 0.000
APACHE II score-median (p25-p75)   9.00 (7.00–11.00) 14.00 (11.00–16.00) 0.001
SOFA score-median (p25-p75)   1.00 (0.00–2.00) 8.00 (6.00–10.00) 0.000
ISTH score-median (p25-p75)   0.00 (0.00–2.00) 3.00 (2.50–4.50) 0.000
JAAM score-median (p25-p75)   1.00 (0.00–2.00) 4.00 (3.00–5.00) 0.000
PT-INR-median (p25-p75)   1.16 (1.12–1.34) 1.41 (1.21–1.66) 0.001
aPTT (seconds)-median (p25-p75)   41.10 (36.10–81.40) 49.40 (41.55–60.85) 0.080
Fibrinogen (g/L)-median (p25-p75)   3.10 (1.96–3.60) 3.94 (2.50–5.88) 0.022
FDP (ug/dl)-median (p25-p75)   5.46 (3.60–13.42) 21.81 (12.24–48.66) 0.000
D-Dimer (ug/ml)-median (p25-p75)   1.71 (0.80–3.58) 4.81 (3.24–10.11) 0.000
Platelet-median*103/mm3 (p25-p75)   157.00 (136.00–191.00) 136.00 (77.00–214.50) 0.305
Leukocytes-median*103/mm3 (p25-p75)   7.87 (5.28–11.90) 10.62 (7.50–15.44) 0.030
Lactate (mmol/L)-median (p25-p75)   1.50 (0.90–1.80) 2.00 (1.30–3.90) 0.006
28 days mortality (%)   0/19 (0) 20/49 (40.82) 0.000
Length of stay in the ICU (days)-median (p25-p75)   3.74 (3–5) 21.57 (13–28) 0.000
AKI-n (%)   0/19 (0) 16/49 (32.65) 0.000
Sepsis-induced liver injury-n (%)   0/19 (0) 3/49 (6.12) 0.277
ARDS-n (%)   0/19 (0) 21/49 (42.86) 0.000
PaO2/FiO2 ratio-median(p25-p75)   318.9 (300–330) 234.1 (170–300) 0.000
Subtotal gastrectomy-n(%)   3/19 (15.79) 10/49 (20.41) 0.549
Enteroanastomosis-n(%)   8/19 (42.11) 19/49 (38.77) 0.805
Cholecystectomy-n(%)   3/19 (15.79) 8/49 (16.33) 0.958
Choledocholithotomy-n(%)   5/19 (26.31) 12/49 (24.49) 0.878
  1. SWS Surgical patients without sepsis, SS Surgical sepsis patients, p 25–75 Percentile 25th–75th, APACHE II Acute Physiology and Chronic Health Evaluation II, SOFA Sepsis-related Organ Failure Assessment, ISTH International Society on Thrombosis and Haemostasis, JAAM Japanese Association for Acute Medicine, PT-INR Prothrombin time international normalized ratio, aPTT Activated partial thromboplastin time, FDP Fibrinogen degradation product, AKI Acute kidney injury, ARDS Acute respiratory distress syndrome, PaO2/FiO2 Pressure of arterial oxygen/fraction inspired oxygen