Negative central venous to arterial lactate gradient in patients receiving vasopressors is associated with higher ICU 30-day mortality: a retrospective cohort study

Table 3 Factors that associated with sustained negative VALac in multivariable logistic regression

Factor	Odds ratio	95% CI	P value
Arterial lactate in first paired blood gas	1.24	1.16, 1.31	< 0.001
24-h lactate clearance (per 10 percentage points change)	0.97	0.95, 0.99	0.016
Epinephrine use	0.36	0.19, 0.70	0.002
ECMO initiation	6.15	1.30, 29.1	0.022
Mean PEEP level	1.16	1.03, 1.31	0.016

Abbreviation: VALac Central venous to arterial lactate level difference, CI Confidence interval, ECMO Extracorporeal membranous oxygenation, PEEP Positive end expiratory pressure

ISSN: 1471-2253