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Fig. 2 | BMC Anesthesiology

Fig. 2

From: Comparison of the in-vivo effect of two tranexamic acid doses on fibrinolysis parameters in adults undergoing valvular cardiac surgery with cardiopulmonary bypass - a pilot investigation

Fig. 2

Concentration curves of Coagulation proteins at different sample points between the three groups. PAI-1: plasminogen activator inhibitor-1, TAFI: thrombin activatable fibrinolysis inhibitor, PAP: plasmin-antiplasmin complex, tPA: tissue plasminogen activator, TM: thrombomodulin. T1: per-operatively before TXA injection (baseline); T2: 5 min after TXA bolus administration (bolus); T3: 5 min after the onset of CPB (CPB); T4: 5 min before the end of CPB (End of CPB); T5: 5 min after protamine injection (protamine). *: Low-dose group compared with placebo group; §: High-dose group compared with Low-dose group

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