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Table 2 Perioperative variables

From: Intraoperative hypotension during liver transplant surgery is associated with postoperative acute kidney injury: a historical cohort study

Variables

No AKI

(N = 88)

AKI

(N = 117)

p-value*

Mean MAP (mmHg)

78 ± 7

72 ± 6

< 0.001

Duration of IOHa

 • Quartile 1 (< 8.6%) (%)

 • Quartiles 2–3 (8.6–39.5%) (%)

 • Quartile 4 (> 39.5%) (%)

44 (50)

37 (42)

7 (8)

8 (7)

65 (55)

44 (38)

< 0.001

Anaesthesia duration (min)

460 [411–536]

500 [453–583]

0.39

Surgical duration (min)

333 [294–385]

376 [324–438]

0.076

Venous bypass (%)

3 (3)

5 (4)

0.53

Portal ischaemia (min)

378 [319–458]

420 [360–495]

0.047

Arterial ischaemia (min)

28 [24-35]

33 [26-43]

0.25

Crystalloids (mL)

2500 [1500–4150]

2100 [1500–3774]

0.25

Colloids (mL)

650 [0-1075]

900 [300–1500]

0.30

Packed red blood cells (mL)

271 [0-1034]

753 [241–1339]

0.013

Cell saver (mL)

211 [0-710]

479 [0-956]

0.064

Total IN (mL)

6157 [4041–9726]

8068 [5285–11,517]

0.015

Estimated blood loss (mL)

2000 [1025–3000]

2700 [1500–5000]

0.006

Diuresis (mL)

368 [203–733]

259 [158–425]

0.26

Total OUT (mL)

2338 [1650–3304]

3050 [1793–5285]

0.011

Intraoperative net fluid balance (mL)

3660 [2028–5825]

4684 [2551–7764]

0.087

Fluid balance at POD#1 (mL)

1204 [188–2813]

2899 [1587–4534]

0.002

Combined fluid balance (mL)b

4926 [3103–8674]

8369 [4944–11,308]

0.003

Calculated blood loss (mL) at POD#2

777 [535–1450]

1222 [698–2080]

0.010

Mean central venous pressure > 8 mmHgc

50 (58)

75 (64)

0.336

Use of vasopressors

85 (97)

117 (100)

0.044

  1. * univariate analysis
  2. IOH intraoperative hypotension; POD#1 postoperative day 1; POD#2 postoperative day 2
  3. apercentage of surgical time spent with a MAP < 65 mmHg (see text for details)
  4. bcombined fluid balance is the combination of intraoperative fluid balance and fluid balance on POD#1
  5. cmean central venous pressure is the average of all values over the surgery
  6. “Total IN” is the sum of crystalloid, colloid, packed red blood cells and cell saver administration and “total OUT” is the sum of estimated blood loss and urine output. Net fluid balance is the difference total IN – total OUT
  7. Data are expressed as mean ± standard deviation, median and [25th -75th ] percentiles or number and percentage (%)