Table 3 Intraoperative clinical data
Variable | Lidocaine group n = 35 | Control group n = 36 | p-value |
|---|---|---|---|
Mean arterial pressure | |||
Mean ± SD | 68.71 ± 6.51 | 71.83 ± 7.10 | 0.07 |
Heart rate | |||
Mean ± SD | 86.31 ± 12.80 | 90.10 ± 16.03 | 0.28 |
Bispectral index | |||
Median (IQR) | 44 (42–46) | 44 (42–45) | 0.23 |
Duration of surgery (min) | |||
Median (IQR) | 58 (48–85) | 64 (46.5–89) | 0.62 |
Duration of anesthesia (min) | |||
Median (IQR) | 86 (71–114) | 90 (74–109.5) | 0.39 |
Time from the end of surgery (“last strip”) to extubation | |||
Median (IQR) | 8 (4–12) | 8 (5.5–12) | 0.79 |
Fentanyl before intubation | |||
[μg] Median (IQR) | 120.0 (90–150) | 115.0 (77.5–190) | 0.85 |
[μg/kg] Median (IQR) | 3.0 (2.857–3.077) | 2.975 (2.857–3.06) | 0.81 |
Fentanyl before skin incision | |||
[μg] Median (IQR) | 80.0 (50–100) | 80.0 (55–100) | 0.94 |
[μg/kg] Median (IQR) | 2.0 (1.852–2.105) | 1.961 (1.89–2.067) | 0.84 |
Cumulative dose of additional fentanyl | |||
[μg] Median (IQR) | 0.0 (0–30) | 40.0 (0–67.5) | < 0.01 |
[μg/kg] Median (IQR) | 0.0 (0.0–0.952) | 0.99 (0.0–1.809) | 0.01 |
Total dose of fentanyl | |||
[μg] Median (IQR) | 200.0 (160–280) | 240.0 (160–337.5) | 0.52 |
[μg/kg] Median (IQR) | 5.091 (4.848–5.714) | 5.969 (5–6.748) | 0.03 |
Number of patients who received additional fentanyl dose | |||
Number (%) | 11 (31.43%) | 24 (66.67%) | < 0.01 |
Amount of oxygen used | |||
[L] Median (IQR) | 121.2 (98.4–142.41) | 122.98 (101.1–145.9) | 0.91 |
Amount of air used | |||
[L] Median (IQR) | 250.96 (214.0–316.22) | 255.0 (204.3–327.75) | 0.92 |
Amount of sevoflurane used | |||
[mL] Median (IQR) | 32.5 (25.0–43.0) | 35.0 (23.5–46.0) | 0.56 |
[mL/h] Median (IQR) | 30.53 (25.7–33.3) | 30.9 (27.6–36) | 0.52 |