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Table 5 Average per patient opioid consumption in PACU and up to 48 h after lumpectomy/mastectomy

From: What is the role of locoregional anesthesia in breast surgery? A systematic literature review focused on pain intensity, opioid consumption, adverse events, and patient satisfaction

  PACU Up to 48 h
Group I Group C p Group I Group C p
Campbell et al., 2014 [10]   3.42 7.33a  
Couceiro et al., 2014 [11]
Cros et al., 2018 [12] 1.5 3 1.5 3
Ferreira Laso et al., 2014 [13] 0 0.7a 0 0.7a
Gürkan et al., 2018 [14] 1 1 5 16a
Ilfeld et al., 2014 [15] 1 2.4a 2.5 5.7
Lanier et al., 2018 [16] 8 17 4 5.18
Mohamed et al., 2013 [17] 0.58 1a
Neethu et al., 2018 [18] 1.46 2.03a
Terkawi et al., 2014 [19] 9.35 9.69 11.02 11.61
Versyck et al., 2017 [20] 0.18 0.33a 0.20 0.37a
Wang et al., 2018 [21] 1.75 5.42a
Wang et al., 2019 [22]
Yao et al., 2019 [23] 0.73 1.03a
TOTAL 3.0 ± 3.63 4.87 ± 5.76 0.51 2.68 ± 0.88 4.94 ± 4.61 0.18
  1. a Difference statistically significant