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Table 2 Studies characteristics

From: What is the role of locoregional anesthesia in breast surgery? A systematic literature review focused on pain intensity, opioid consumption, adverse events, and patient satisfaction

Author, year Study Sites No. Type of surgery Anesthesia Intervention
A. LUMPECTOMY/MASTECTOMY
Campbell et al.,[10] 2014 SB-RCT New Zeland, 1 79 Lumpectomy/Mastectomy ± ALND ? Local Infiltration
Couceiro et al.,[11] 2014 DB-RCT Brazil, 1 44 Mastectomy GA IV lidocaine
Cros et al.,[12] 2018 DB-RCT France, 1
Canada, 1
127 Lumpectomy/Mastectomy ± SLNB/ALND GA Pecs I
Ferreira Laso et al.,[13] 2014 DB-RCT Spain, 1 73 Mastectomy GA Infusion pump
Gürkan et al.,[14] 2018 SB-RCT Turkey,? 50 Lumpectomy/Mastectomy ± SLNB/ALND GA ESP
Ilfeld et al.,[15] 2014 DB-RCT US,? 60 Mastectomy ± ALND Sedation PVB
Lanier et al .[16]2018 DB-RCT US,? 45 Mastectomy + reconstruction ± SLNB/ALND ? Intercostal + pectoral nerve blocks
Mohamed et al.,[17] 2013 DB-RCT Egypt,? 140 Mastectomy ± ALND GA Local infiltration
Neethu et al.,[18] 2018 RCT India, 1 60 Mastectomy ± SLNB/ALND GA Pecs I - II
Terkawi et al.,[19]2014 DB-RCT US,? 71 Mastectomy GA IV lidocaine
Versyck et al.,[20] 2017 DB-RCT Belgium, 1 140 Mastectomy/tumorectomy ±SLNB/ALND GA Pecs II
Wang et al.,[21] 2018 SB-RCT China,? 64 Mastectomy + reconstruction ± ALND GA Pecs II
Wang et al.,[22] 2019 RCT China,? 61 Mastectomy GA Pecs I + SPB
Yao et al.,[23] 2019 DB-RCT China, 1 72 Mastectomy ± ALND GA SPB
B. BREAST AUGMENTATION
Gardiner et al.,[24] 2012 SB-RCT Australia,? 40 BA Sedation PVB
Picard et al.,[25] 2017 SB-RCT France,? 72 BA ? Local infiltration
Schuitemaker et al.,[26] 2019 DB-RCT Spain,? 30 BA GA Pecs II + SPB
C. BREAST REDUCTION
Christie et al., [27] 2017 DB-RCT US, 1 40 BR GA Tumescent Anaesthesia
Valente et al.,[28] 2014 DB-RCT Brazil,? 39 BR GA Local infiltration
  1. SB-RCT Single-Blind Randomized Controlled Trial, DB-RCT Double-Blind Randomized Controlled Trial, SLNB Sentinel Lymph Node Biopsy, ALND Axillary Lymph Node Dissection, GA General Anesthesia, Pecs Pectoralis nerve block, ESP Erector Spinae Plane block, PVB ParaVertebral Block, SPB Serratus Plane Block, BA Breast Augmentation, BR Breast Reduction;?, not reported