Table 1 pH and percentage of the original propofol remaining when mixed with water and saline solution
|  | 10 μg mL− 1 | 20 μg mL− 1 | 30 μg mL− 1 | 40 μg mL− 1 | 50 μg mL− 1 | |||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 h | 6 h | 12 h | 24 h | 1 h | 6 h | 12 h | 24 h | 1 h | 6 h | 12 h | 24 h | 1 h | 6 h | 12 h | 24 h | 1 h | 6 h | 12 h | 24 h | |
Percent Propofol Remaining when left in Isolation (mean ± SEM; n = 3) | ||||||||||||||||||||
I | 102.3 ± 0.90 | 101.1 ± 1.03 | 100.5 ± 1.05 | 100.2 ± 1.04 | 102.3 ± 0.90 | 101.1 ± 1.03 | 100.5 ± 1.05 | 100.2 ± 1.04 | 102.3 ± 0.90 | 101.1 ± 1.03 | 100.5 ± 1.05 | 100.2 ± 1.04 | 102.3 ± 0.90 | 101.1 ± 1.03 | 100.5 ± 1.05 | 100.2 ± 1.04 | 102.3 ± 0.90 | 101.1 ± 1.03 | 100.5 ± 1.05 | 100.2 ± 1.04 |
W | 101.1 ± 0.22 | 100.4 ± 2.37 | 100.6 ± 2.00 | 99.6 ± 1.94 * | 102.2 ± 2.27 | 102.1 ± 1.92 | 101.8 ± 1.48 | 101.6 ± 1.58 | 99.8 ± 0.20 a | 100.5 ± 0.54 d | 100.9 ± 0.35 d | 99.5 ± 0.72 | 101.6 ± 2.06 | 100.5 ± 1.80 | 100.3 ± 1.69 | 99.4 ± 1.56 | 99.8 ± 0.13 * a | 98.7 ± 0.21 * | 98.2 ± 0.13 | 98.0 ± 0.21 |
0.9% | 99.9 ± 0.48 | 99.4 ± 0.48 b | 98.6 ± 0.18 * b | 98.3 ± 0.27 | 100.5 ± 0.07 * d | 101.9 ± 0.15 * | 100.5 ± 0.39 | 99.1 ± 0.33 | 101.2 ± 0.32 ** d | 100.7 ± 0.89 | 99.5 ± 0.54 | 97.9 ± 0.12 b | 101.1 ± 0.78 | 98.9 ± 0.86 b | 97.9 ± 0.60 * b | 98.0 ± 0.54 * | 99.4 ± 0.12 # | 98.8 ± 0.28 * b | 98.1 ± 0.29 b | 98.0 ± 0.06 b |
20% | 100.0 ± 0.49 | 100.0 ± 0.48 d | 99.3 ± 0.06 d | 98.1 ± 0.10 b | 100.1 ± 0.12 | 99.7 ± 0.48 d | 99.3 ± 0.24 d | 98.9 ± 0.15 | 98.7 ± 0.58 # | 100.8 ± 0.59 d | 100.1 ± 0.83 | 99.0 ± 0.88 | 99.5 ± 0.19 # | 100.7 ± 0.16 d | 101.3 ± 0.37 a, b, d | 100.9 ± 0.32 a, b, d | 99.1 ± 0.15 # b | 97.9 ± 0.13 # | 97.9 ± 0.33 | 97.8 ± 0.41 |
pH of Solution (mean ± SEM; n = 3) | ||||||||||||||||||||
I | 7.69 ± 0.01 | 7.70 ± 0.02 | 7.76 ± 0.01 | 7.74 ± 0.00 | 7.69 ± 0.01 | 7.70 ± 0.02 | 7.76 ± 0.01 | 7.74 ± 0.00 | 7.69 ± 0.01 | 7.70 ± 0.02 | 7.76 ± 0.01 | 7.74 ± 0.00 | 7.69 ± 0.01 | 7.70 ± 0.02 | 7.76 ± 0.01 | 7.74 ± 0.00 | 7.69 ± 0.01 | 7.70 ± 0.02 | 7.76 ± 0.01 | 7.74 ± 0.00 |
W | 7.69 ± 0.01 | 7.72 ± 0.03 d | 7.80 ± 0.03 | 7.78 ± 0.03 | 7.74 ± 0.01 # | 7.78 ± 0.02 d | 7.83 ± 0.03 | 7.81 ± 0.02 | 7.76 ± 0.01 # | 7.79 ± 0.02 d | 7.85 ± 0.02 | 7.82 ± 0.03 # | 7.70 ± 0.01 | 7.75 ± 0.02 d | 7.80 ± 0.03 | 7.78 ± 0.03 | 7.67 ± 0.02 | 7.61 ± 0.02 # | 7.65 ± 0.05 | 7.67 ± 0.03 |
0.9% | 7.65 ± 0.01 | 7.52 ± 0.03 ^ | 7.48 ± 0.00 ^ | 7.43 ± 0.01 ^ | 7.47 ± 0.04 ^ a, d | 7.46 ± 0.02 ^ | 7.46 ± 0.02 ^ | 7.36 ± 0.01 ^ a | 7.44 ± 0.02 ^ a, d | 7.45 ± 0.02 ^ | 7.52 ± 0.04 ^ | 7.34 ± 0.01 ^ a | 7.42 ± 0.02 ^ a, d | 7.21 ± 0.02 ^ a,b,c | 7.26 ± 0.02 ^ a,b,c | 7.24 ± 0.02 ^ a,b,c | 7.22 ± 0.01 ^ a | 7.23 ± 0.02 ^ a,b,c | 7.21 ± 0.01 ^ a,b,c | 7.20 ± 0.02 ^ a,b,c |
20% | 7.09 ± 0.02 ^ | 7.02 ± 0.00 ^ | 7.04 ± 0.01 ^ | 7.07 ± 0.02 ^ | 7.02 ± 0.02 ^ | 6.95 ± 0.01 ^ a | 6.98 ± 0.00 ^ a | 7.01 ± 0.01 ^ | 6.94 ± 0.01 ^ a, b | 6.98 ± 0.02 ^ | 6.98 ± 0.01 ^ a | 6.98 ± 0.01 ^ a | 6.93 ± 0.02 ^ a, b | 6.96 ± 0.01 ^ a | 6.95 ± 0.01 ^ a, b | 6.91 ± 0.01 ^ e | 6.92 ± 0.02 ^ a, b | 6.94 ± 0.00 ^ a | 6.97 ± 0.00 ^ a, b | 6.94 ± 0.00 ^ a,b,c |