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Table 2 Voltage thresholds for supramaximal twitch contraction in vitro

From: Impact of statin intake on malignant hyperthermia: an in vitro and in vivo swine study

 

MHS

MHN

Untreated

Simvastatin

Untreated

Simvastatin

Vastus

6.66 ± 1.1†

6.49 ± 1.6‡

11.9 ± 3.3

9.51 ± 2.4

Rectus

4.80 ± 1.6†

4.78 ± 1.2

10.2 ± 3.4

6.21 ± 2.5§

Diaphragm

7.76 ± 0.9

5.85 ± 1.6§

7.76 ± 1.1

6.73 ± 1.3

  1. Mean ± S.D. n = 8 bundles per group.
  2. †p ≤ 0.001 vs. MHN untreated, ‡p ≤ 0.001 vs. MHN simvastatin, §p ≤ 0.01 vs. untreated
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BMC Anesthesiology

ISSN: 1471-2253

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