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Table 5 Factors associated with risk for PONV until noon the first postoperative day

From: Risk of postoperative nausea and vomiting in hip and knee arthroplasty: a prospective cohort study after spinal anaesthesia including intrathecal morphine

 

Number of

Number of patients

Unadjusted OR

 

patients

with PONV (%)

(CI)

p-value

Gender

 Female

42

20 (48%)

2.33 (1.01–5.38)

0.046

 Male

57

16 (28%)

  

BMI

 < 35 kg/m2

88

30 (34%)

1.93 (0.52–7.20)

0.32

 ≥ 35 kg/m2

10

5 (50%)

  

History of PONV

 Yes

19

13 (68%)

5.37 (1.82–15.8)

0.003

 No

80

23 (29%)

  

History of motion sickness

 Yes

19

8 (42%)

1.35 (0.49–3.75)

0.56

 No

80

28 (35%)

  

Non-smoker

 Yes

98

36 (36%)

NA

0.184

 No

1

1 (100%)

  

Preoperative treatment with opioids

 Yes

12

4 (33%)

0.90 (0.24–3.08)

0.81

 No

87

32 (37%)

  

COX-2 inhibitor in premedication

 Yes

9

3 (33%)

0.86 (0.21–3.68)

0.84

 No

90

33 (37%)

  

Suboptimal PONV prophylaxis

 Yes

27

15 (56%)

3.04 (1.22–7.57)

0.015

 No

72

21 (29%)

  

Type of prosthesis surgery

 Hip

78

27 (35%)

0.71 (0.26–1.88)

0.49

 Knee

21

9 (43%)

  

Intrathecal morphine, dose

 80–100 μg

11

5 (45%)

1.51 (0.42–5.42)

0.79

 120 μg

76

27 (35%)

reference

 

 140–200 μg

12

4 (33%)

0.91 (0.25–3.29)

 

Gabapentin given postoperatively

 Yes

36

13 (39%)

1.22 (0.52–2.88)

0.66

 No

63

23 (35%)

  

Given oral or parenteral opioids until noon Day 1

 Yes

97

35 (36%)

0.56 (0.03–9.3)

0.68

 No

2

1 (50%)

  

Maximal NRS ≥5 for pain until noon Day 1.

 Yes

39

17 (44%)

1.67 (0.72–3.84)

0.23

 No

60

19 (32%)

  
  1. Number of patients is the total number in the subgroup. PONV risk is presented as the number of patients in the subgroup with PONV (%). Unadjusted OR, unadjusted odds ratio; CI 95% confidence interval, NRS Numeric Rating Scale, Day 1 first day after surgery, NA not available for calculation