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Fig. 3 | BMC Anesthesiology

Fig. 3

From: Sevoflurane modulates breast cancer cell survival via modulation of intracellular calcium homeostasis

Fig. 3

Decreased cytosolic Ca2+ concentrations reduce breast cancer cell survival. Chelation of cytosolic Ca2+ with BAPTA-AM dramatically reduced cell survival in both breast cancer lines but not in normal breast tissue. The use of general anesthetics sevoflurane and propofol did not alter this effect. Data represents means ± SD from at least 9 repeats of 3 separate experiments and was analyzed by two-way ANOVA followed by Turkey multiple comparison tests. * P < 0.05, **** P < 0.0001

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