Skip to main content

Table 1 Demographic data of LDKT recipients enrolled into the study. If not indicated otherwise: n (%)

From: Effects of Desflurane and Sevoflurane anesthesia on regulatory T cells in patients undergoing living donor kidney transplantation: a randomized intervention trial

Characteristics Sevoflurane (n = 20) Desflurane (n = 20) P-value
Recipient
 Age (year), mean ± SD 37.6 ± 10.5 42.3 ± 10.6 0.163
 Gender, male 13 (65) 15 (75) 0.490
 BMI (kg/m2), median [IQR] 21.8 [19.2, 24.4] 22.3 [21.5, 25.1] 0.301
 Hypertension 18 (90) 19 (95) 0.999
 Diabetes mellitus 4 (20) 0 (0) 0.106
 ADPKD 1 (5) 0 (0) 0.999
 Hemodialysis 18 (90) 15 (75) 0.407
 Peritoneal dialysis 2 (10) 5 (25) 0.407
 Baseline creatinine (mg/dL), median [IQR] 7.7 [5.4, 11.8] 7.2 [5.2, 12.9] 0.797
 Pretransplant PRA (%), median [IQR] 0 [0, 0] 0 [0, 0] 0.999
 HLA-A + B + DR mismatch, median [IQR] 1 [1, 1.5] 3 [1, 3] 0.371
 White blood cell count (cells/mL), mean ± SD 6130 ± 2157 5838 ± 2072 0.665
 Lymphocyte (%), mean ± SD 21.4 ± 6.7 22.8 ± 9.2 0.586
Donor
 Age (year), mean ± SD 44.8 ± 12.8 36.1 ± 11.3 0.029
 Gender, male 7 (35) 6 (30) 0.736
 Donor warm ischemic time (min), median [IQR] 3.0 [2.0, 4.0] 3.0 [2.0, 5.3] 0.519
 Cold ischemic time (min), median [IQR] 26.5 [18.0, 31.5] 26.5 [19.5, 40.8] 0.432
Protocol immunosuppressive drug
 Tacrolimus 8 (40) 11 (55) 0.342
 Cyclosporin A 3 (15) 2 (10) 0.999
 Tacrolimus plus basiliximab 7 (35) 5 (25) 0.490
 Cyclosporin A plus basiliximab 2 (10) 2 (10) 0.999
Intraoperative variable
 Recipient warm ischemic time (min), median [IQR] 37.5 [31.5, 44.5] 35.5 [30.0, 41.3] 0.647
 Estimated blood loss (mL), mean ± SD 348 ± 124 250 ± 129 0.020
 Intravenous fluid (mL), mean ± SD 3716 ± 869 3968 ± 979 0.396
 Intravenous ephedrine (mg), median [IQR] 0.0 [0.0, 7.5] 0.0 [0.0, 12.8] 0.701
Intravenous anesthesia
 Propofol (mg), median 175.0 [127.5, 200.0 [170.0, 0.26
 [IQR] 200.0] 200.0] 2
 Fentanyl (mcg), median 100.0 [100.0, 100.0 [100.0, 0.76
 [IQR] 150.0] 156.3] 7
 Morphine (mg), median [IQR] 5.5 [3.0, 7.3] 6.0 [3.0, 10.0] 0.678
 Midazolam (mg), median [IQR] 2.0 [0.0, 2.1] 2.0 [0.0, 2.5] 0.650
 Atracurium (mg), median [IQR] 90.0 [80.0, 110.0] 92.5 [85.0, 101.3] 0.643
Anesthesia time (min) 279 ± 42 303 ± 45 0.098
  1. Abbreviations: ADPKD Autosomal dominant polycystic kidney disease, BMI Body mass index, HLA Human leukocyte antigen, PRA Panel reactive antibodies