Table 1 Demographic data of LDKT recipients enrolled into the study. If not indicated otherwise: n (%)

 Age (year), mean ± SD

37.6 ± 10.5

42.3 ± 10.6

0.163

 Gender, male

13 (65)

15 (75)

0.490

 BMI (kg/m²), median [IQR]

21.8 [19.2, 24.4]

22.3 [21.5, 25.1]

0.301

 Hypertension

18 (90)

19 (95)

0.999

 Diabetes mellitus

4 (20)

0 (0)

0.106

 ADPKD

1 (5)

0 (0)

0.999

 Hemodialysis

18 (90)

15 (75)

0.407

 Peritoneal dialysis

2 (10)

5 (25)

0.407

 Baseline creatinine (mg/dL), median [IQR]

7.7 [5.4, 11.8]

7.2 [5.2, 12.9]

0.797

 Pretransplant PRA (%), median [IQR]

0 [0, 0]

0 [0, 0]

0.999

 HLA-A + B + DR mismatch, median [IQR]

1 [1, 1.5]

3 [1, 3]

0.371

 White blood cell count (cells/mL), mean ± SD

6130 ± 2157

5838 ± 2072

0.665

 Lymphocyte (%), mean ± SD

21.4 ± 6.7

22.8 ± 9.2

0.586

 Age (year), mean ± SD

44.8 ± 12.8

36.1 ± 11.3

0.029

 Gender, male

7 (35)

6 (30)

0.736

 Donor warm ischemic time (min), median [IQR]

3.0 [2.0, 4.0]

3.0 [2.0, 5.3]

0.519

 Cold ischemic time (min), median [IQR]

26.5 [18.0, 31.5]

26.5 [19.5, 40.8]

0.432

 Tacrolimus

8 (40)

11 (55)

0.342

 Cyclosporin A

3 (15)

2 (10)

0.999

 Tacrolimus plus basiliximab

7 (35)

5 (25)

0.490

 Cyclosporin A plus basiliximab

2 (10)

2 (10)

0.999

 Recipient warm ischemic time (min), median [IQR]

37.5 [31.5, 44.5]

35.5 [30.0, 41.3]

0.647

 Estimated blood loss (mL), mean ± SD

348 ± 124

250 ± 129

0.020

 Intravenous fluid (mL), mean ± SD

3716 ± 869

3968 ± 979

0.396

 Intravenous ephedrine (mg), median [IQR]

0.0 [0.0, 7.5]

0.0 [0.0, 12.8]

0.701

 Propofol (mg), median

175.0 [127.5,

200.0 [170.0,

0.26

 [IQR]

200.0]

200.0]

2

 Fentanyl (mcg), median

100.0 [100.0,

100.0 [100.0,

0.76

 [IQR]

150.0]

156.3]

7

 Morphine (mg), median [IQR]

5.5 [3.0, 7.3]

6.0 [3.0, 10.0]

0.678

 Midazolam (mg), median [IQR]

2.0 [0.0, 2.1]

2.0 [0.0, 2.5]

0.650

 Atracurium (mg), median [IQR]

90.0 [80.0, 110.0]

92.5 [85.0, 101.3]

0.643

Anesthesia time (min)

279 ± 42

303 ± 45

0.098