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Table 2 Intraoperative Data

From: The effect of intraoperative goal-directed crystalloid versus colloid administration on perioperative inflammatory markers - a substudy of a randomized controlled trial

 

Crystalloids

(n = 58)

Colloids

(n = 62)

p - Value

Duration of Anesthesia, min

330 ± 121

307 ± 117

0.29

Duration of Surgery, min

281 ± 118

250 ± 113

0.14

Fluid management

 Total Fluid Intake, mLa

4519 (3382–4824)

3247 (2495–4210)

<  0.001°

 Crystalloid, mL

3905 (2880–5288)

1557 (1207–2116)

<  0.001°

 Colloid, mL

0 (0–0)

1250 (750–1938)

<  0.001°

 Estimated Blood Loss, mL

500 (100–1000)

400 (100–875)

0.23

 Transfusion yes/no (%)

3/55 (5/95)

6/56 (10/90)

0.58

 Urinary Output, mL

350 (300–500)

405 [250, 615]

0.82

Anesthesia Management

 Fentanyl, mcg

1000 [800, 1200]

850 (623–1223)

0.39

 TWA Et Sevoflurane, %

1.8 (1.6–1.9)

1.8 (1.6–2.0)

0.88

 Core Temperature, °C

36.4 ± 0.4

36.4 ± 0.5

0.98

 ICU Admission yes/no (%)

36/22 (62/38)

36/26 (58/42)

0.71

Hemodynamic

 TWA MAP, mmHg

77 ± 6

75 ± 8

0.77

 TWA HR, beats.min−1

73 ± 12

70 ± 11

0.30

 TWA FTc, ms

339 (321–353)

348 (334–364)

0.009°

 TWA SV, mL

76 (64–90)

91 (75–106)

< 0.001°

 TWA CO, L.min− 1

5.4 ± 1.2

6.2 ± 1.5

0.002°

 Phenylephrine yes/no (%)

54/4 (93/7)

53/9 (85/15)

0.24

  1. Intraoperative data are presented as means ± SD, medians (IQR) or as counts for the categorical outcomes. Means were compared with an unpaired two-sided t-tests or Mann-Whitney-U tests as appropriate, medians with Wilcoxon rank-sum tests and counts with chi-square or Fisher’s exact tests. ° represents statistical significance (P < 0.05)
  2. Abbreviations: Et end tidal, ICU intensive care unit, TWA time weighted average, MAP mean arterial pressure, HR heart rate, FTc corrected flow time, SV stroke volume, CO cardiac output, SD standard deviation
  3. a Total fluid intake includes baseline, fluid boluses, antibiotics, analgesics and additional fluid, administered at the discretion of attending anesthesiologist