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Table 3 Association between variables and 180-day postoperative mortality

From: The cumulative duration of bispectral index less than 40 concurrent with hypotension is associated with 90-day postoperative mortality: a retrospective study

Variables

Univariable association

Multivariable association

OR

95% CI

P-valuea

OR

95% CI

P-valueb

Age (year)

1.03

1.01–1.06

.007

  

.358

Male sex

1.52

0.87–2.64

.141

  

.243

Body mass index (kg/m2)

0.86

0.79–9.34

<.001

  

.230

Category of surgeryb (vs. Stomach)

  

.007

  

.008

 Colorectalb

2.75

1.31–5.77

.008

3.34

1.51–7.39

.003

 Hepatic

2.18

0.76–6.21

.146

1.90

0.63–5.72

.260

 Biliary-pancreas

0.99

0.39–2.52

.983

1.23

0.46–3.30

.678

Volatile agent compared with TIVA

0.83

0.50–1.50

.492

   

Duration of anesthesia (min)

1.00

0.99–1.00

.718

   

bis40_dur (min)

1.00

0.99–1.00

.876

   

bis40_5min

1.31

0.47–3.67

.605

   

bis20_dur (min)

0.99

0.90–1.09

.791

   

bis20_5min

1.88

0.44–8.04

.393

   

eegsup_dur (min)

1.01

0.97–1.04

.745

   

eegsup_5min

1.20

0.47–3.06

.700

   

bis40map50_dur (min)

1.22

1.03–1.44

.018

  

.767

bis20map50_dur (min)

1.45

0.33–6.25

.622

   

map50_dur (min)

1.05

0.93–1.18

.452

   

Past medical history

 Aortic stenosis

3.44

0.43–27.58

.245

   

 Congestive heart failure

< 0.01

 

.999

   

 Coronary artery disease

0.62

0.15–2.59

.516

   

 Hypertension

1.21

0.72–2.05

.474

   

 Peripheral vascular occlusive disease

< 0.01

 

.999

   

 Dysrhythmiab

4.36

1.89–10.04

.001

3.43

1.31–9.00

.012

 Chronic obstructive pulmonary disease

1.40

0.33–5.93

.645

   

 Pulmonary hypertension

5.16

0.61–43.59

.131

  

.563

 Stroke

0.43

0.06–3.17

.410

   

 Malignancyb

5.13

1.85–14.23

.002

3.08

1.05–9.03

.040

 Diabetes

2.09

1.21–3.61

.008

  

.540

 Sleep apnea

< 0.01

 

.999

   

Current smoker

1.14

0.55–2.35

.723

   

Regular alcohol ingestion

0.71

0.37–1.39

.320

   

ASA (compared with ASA I)

  

<.001

  

.055

 II

7.55

1.81–31.41

.005

3.17

0.73–13.70

.122

 IIIb

21.35

4.93–92.53

<.001

6.21

1.36–28.31

.018

 IV

< 0.01

 

.999

0.00

0.00

.999

Hemoglobinb level (g/dL)

0.56

0.48–0.65

<.001

0.79

0.66–0.95

.014

Albuminb level (g/dL)

0.11

0.07–0.18

<.001

0.18

0.10–0.32

.000

  1. aAfter binary logistic regression in ‘enter’ method, variables yielding P-values under 0.2 were regarded to be potential risk factors. bIn the final multivariable logistic regression analysis in ‘backward LR’ method, variables remaining in final model were regarded as significant risk factors
  2. Abbreviations: OR Odds ratio; CI Confidence interval; TIVA Total intravenous anesthesia; BIS Bispectral index; bis40_dur, cumulative time in which BIS < 40; bis40_5min, incidence in which cumulative time of BIS < 40 lasted > 5 min; bis20_dur, cumulative time in which BIS < 20; bis20_5min, incidence in which cumulative time of BIS < 20 lasted > 5 min; EEG Electroencephalogram; eegsup_dur, cumulative time in which patient’s EEG was suppressed; eegsup_5min, incidence in which cumulative time of EEG suppression lasted > 5 min; MAP Mean arterial pressure; bis40map50_dur, cumulative time that BIS < 40 and MAP < 50 mmHg simultaneously; bis20map50_dur, cumulative time that BIS < 20 and MAP < 50 mmHg simultaneously; map50_dur, cumulative time that MAP < 50 mmHg; ASA The American Society of Anesthesiologists physical status