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Table 2 Study primary and secondary endpoints among baseline (standard ETT) and intervention (TaperGuard™ ETT) cohorts. Data are expressed as mean (standard deviation) unless otherwise specified

From: Implementation of the TaperGuard™ endotracheal tube in an unselected surgical population to reduce postoperative pneumonia

Characteristics

Baseline (n = 9037)

Intervention (n = 6351)

Baseline vs. Intervention (95% Confidence Interval)

p value

Ventilator associated pneumoniaa, n (%)

162 (1.79)

103 (1.62)

  

 Unadjusted OR

  

0.90 (0.70, 1.16)

0.423

 Adjusted OR c

  

0.90 (0.69, 1.19)

0.469

Duration of mechanical ventilationb, min

208.9 (112.6)

210.9 (112.2)

  

 Unadjusted difference

  

2.0 (−2.0, 6.0)

0.333

 Adjusted differencec

  

1.6 (−2.7, 5.9)

0.476

Hospital length of stay, days

6.2 (7.9)

6.8 (9.1)

  

 Unadjusted difference

  

0.6 (0.3, 0.9)

< 0.001

 Adjusted differencec

  

0.5 (0.2, 0.8)

< 0.001

Hospital mortality, n (%)

92 (1.0)

94 (1.5)

1.46 (1.09, 1.95)

0.010

 Unadjusted OR

  

1.40 (1.02, 1.93)

0.039

 Adjusted ORc

    
  1. ASA American Society of Anesthesiologists, NMB neuromuscular blockade, PEEP positive end expiratory pressure
  2. aSummaries are odds ratios (OR) for VAP: Intervention compared with baseline
  3. bSummaries are mean differences (Diff): Intervention compared with baseline
  4. cAdjustment variables are: ASA status (1–5), Tidal Volume (ml/kg), Caucasian race (yes, no), age (years), male gender (yes, no), PEEP (0 and > 0)