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Table 3 Clinical Outcomes of the Patients According to Subgroups

From: Intraoperative mechanical ventilation practice in thoracic surgery patients and its association with postoperative pulmonary complications: results of a multicenter prospective observational study

 

All Patients

(n = 302)

OLV

(n = 168)

TLV

(n = 134)

p value

Endoscopic

(n = 46)

Open

(n = 256)

p value

Low Risk

(n = 38)

High Risk

(n = 264)

p value

Primary outcome

PPC

138 (45.7)

82 (48.8)

56 (41.8)

0.223

16 (34.8)

122 (47.7)

0.106

11 (28.9)

127 (48.1)

0.026

 Need of oxygen

109 (36.1)

65 (38.9)

44 (32.8)

0.274

12 (26.1)

97 (38.0)

0.120

8 (21.1)

101 (38.4)

0.037

 Respiratory failure

26 (8.6)

15 (8.9)

11 (8.2)

0.824

1 (2.2)

25 (9.8)

0.148

2 (5.3)

24 (9.1)

0.755

 Invasive MV

26 (8.6)

14 (8.3)

12 (9.0)

0.848

3 (6.5)

23 (9.0)

0.778

1 (2.6)

25 (9.5)

0.222

 NIV

15 (5.0)

10 (6.0)

5 (3.7)

0.377

2 (4.3)

13 (5.1)

1.000

1 (2.6)

14 (5.3)

0.702

 ARDS

4 (1.3)

4 (2.4)

0 (0.0)

0.132

0 (0.0)

4 (1.6)

1.000

0 (0.0)

4 (1.5)

1.000

 Pneumonia

8 (2.6)

6 (3.6)

2 (1.5)

0.307

2 (4.3)

6 (2.3)

0.350

1 (2.6)

7 (2.7)

1.000

Secondary outcomes

Severe PPCa

53 (17.5)

30 (17.9)

23 (17.2)

0.875

7 (15.2)

46 (18.0)

0.651

4 (10.5)

49 (18.6)

0.223

Intra-OP complications

 Desaturation

61 (20.2)

38 (22.6)

23 (17.2)

0.240

7 (15.2)

54 (21.1)

0.360

5 (13.2)

56 (21.2)

0.247

 Unplanned RM

48 (15.9)

31 (18.5)

17 (12.7)

0.173

7 (15.2)

41 (16.0)

0.891

3 (7.9)

45 (17.0)

0.149

 Pressure reduction

36 (11.9)

27 (16.1)

9 (6.7)

0.012

5 (10.9)

31 (12.1)

0.811

2 (5.3)

34 (12.9)

0.281

 Flow limitation

3 (1.0)

2 (1.2)

1 (0.8)

1.000

0 (0.0)

3 (1.2)

1.000

0 (0.0)

3 (1.1)

1.000

 Hypotension

102 (33.8)

60 (35.7)

42 (31.3)

0.424

8 (17.4)

94 (36.7)

0.010

3 (7.9)

99 (37.5)

<  0.001

 Vasopressors

113 (37.4)

65 (38.7)

48 (35.8)

0.608

13 (28.3)

100 (39.1)

0.163

3 (7.9)

110 (41.7)

<  0.001

 New arrhythmias

6 (2.0)

3 (1.8)

3 (2.2)

1.000

0 (0.0)

6 (2.3)

0.595

0 (0.0)

6 (2.3)

1.000

ICU admissionb

6 (2.0)

2 (1.2)

4 (3.0)

0.411

0 (0.0)

6 (2.3)

0.595

0 (0.0)

6 (2.3)

1.000

Hospital LOS, days

6.0 (3.0–10.0)

6.0 (4.0–11.0)

5.0 (3.0–9.0)

0.010c

3.0 (1.0–7.5)

6.0 (4.0–10.0)

< 0.001c

4.0 (1.0–6.0)

6.0 (4.0–10.0)

< 0.001c

Hospital mortality

1 (0.3)

1 (0.6)

0 (0.0)

1.000

0 (0.0)

1 (0.4)

1.000

0 (0.0)

1 (0.4)

1.000

  1. Values are presented as median (interquartile range) or number (percentage). p values from a Proportions χ2 or Fisher exact tests for proportions and Mann-Whitney U Test for continuous variables ARDS Acute respiratory distress syndrome, ICU Intensive care unit, Intra-OP Intraoperative, LOS Length of stay, MV Mechanical ventilation, NIV Non-invasive ventilation, OLV One lung ventilation, PPC Postoperative pulmonary complication, RM Recruitment maneuvers, TLV Total lung ventilation
  2. aexcluding need of oxygen
  3. bunplanned admission
  4. cp value from the Cox proportional hazard model
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BMC Anesthesiology

ISSN: 1471-2253

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