| All Patients (n = 302) | OLV (n = 168) | TLV (n = 134) | p value | Endoscopic (n = 46) | Open (n = 256) | p value | Low Risk (n = 38) | High Risk (n = 264) | p value |
---|---|---|---|---|---|---|---|---|---|---|
Age, years | 62.0 (50.0–70.8) | 62.0 (50.0–70.0) | 62.0 (47.2–71.0) | 0.799 | 62.0 (49.8–70.8) | 62.0 (50.0–70.2) | 0.839 | 37.0 (28.2–46.0) | 64.0 (54.8–71.2) | <  0.001 |
Male gender | 181 (59.9) | 101 (60.1) | 80 (59.7) | 0.941 | 23 (50.0) | 158 (61.7) | 0.135 | 17 (44.7) | 164 (62.1) | 0.040 |
BMI, kg/m2 | 25.6 (22.9–28.9) | 25.7 (23.3–29.3) | 25.4 (22.5–28.7) | 0.398 | 25.1 (21.8–27.5) | 25.7 (23.0–29.3) | 0.129 | 23.1 (20.9–26.3) | 25.8 (23.4–29.2) | 0.010 |
ASA physical status |  |  |  | 0.573 |  |  | 0.880 |  |  | <  0.001 |
 1 | 40 (13.3) | 22 (13.1) | 18 (13.5) |  | 5 (11.1) | 35 (13.7) |  | 20 (54.1) | 20 (7.6) |  |
 2 | 109 (36.2) | 60 (35.7) | 49 (36.8) |  | 18 (40.0) | 91 (35.5) |  | 17 (45.9) | 92 (34.8) |  |
 3 | 141 (46.8) | 82 (48.8) | 59 (44.4) |  | 20 (44.4) | 121 (47.3) |  | 0 (0.0) | 141 (53.4) |  |
 4 | 11 (3.7) | 4 (2.4) | 7 (5.3) |  | 2 (4.4) | 9 (3.5) |  | 0 (0.0) | 11 (4.2) |  |
ARISCAT score | 40.0 (27.0–49.5) | 40.0 (27.0–47.0) | 39.0 (27.0–50.0) | 0.755 | 35.0 (27.0–43.0) | 40.0 (27.0–50.0) | 0.018 | 24.0 (24.0–24.0) | 43.0 (27.0–50.0) | < 0.001 |
Functional status | ||||||||||
 Independent | 270 (89.4) | 153 (91.1) | 117 (88.0) | 0.536 | 43 (93.5) | 227 (89.0) | 0.438 | 36 (94.7) | 234 (89.0) |  |
 Partially dependent | 26 (8.6) | 12 (7.1) | 14 (10.5) |  | 2 (4.3) | 24 (9.4) |  | 2 (5.3) | 24 (9.1) | 0.772 |
 Totally dependent | 5 (1.7) | 3 (1.8) | 2 (1.5) |  | 1 (2.2) | 4 (1.6) |  | 0 (0.0) | 5 (1.9) |  |
Smoking | 83 (27.5) | 43 (25.6) | 40 (29.9) | 0.410 | 12 (26.1) | 71 (27.7) | 0.817 | 9 (23.7) | 74 (28.0) | 0.574 |
Transfusion (<  24 h) | 6 (2.0) | 2 (1.2) | 4 (3.0) | 0.411 | 0 (0.0) | 6 (2.3) | 0.595 | 0 (0.0) | 6 (2.3) | 1.000 |
Respiratory infection (<  30 d) | 24 (7.9) | 17 (10.1) | 7 (5.2) | 0.118 | 2 (4.3) | 22 (8.6) | 0.551 | 0 (0.0) | 24 (9.1) | 0.054 |
Recent MV (<  30 d) | 8 (2.6) | 5 (3.0) | 3 (2.2) | 1.000 | 0 (0.0) | 8 (3.1) | 0.612 | 0 (0.0) | 8 (3.0) | 0.602 |
Co-morbidities | ||||||||||
 COPD | 54 (17.9) | 35 (20.8) | 19 (14.2) | 0.133 | 6 (13.0) | 48 (18.8) | 0.352 | 1 (2.6) | 53 (20.1) | 0.005 |
 Apnea | 5 (1.7) | 1 (0.6) | 4 (3.0) | 0.174 | 1 (2.2) | 4 (1.6) | 0.564 | 0 (0.0) | 5 (1.9) | 1.000 |
 Liver cirrhosis | 2 (0.7) | 2 (1.2) | 0 (0.0) | 0.504 | 0 (0.0) | 2 (0.8) | 1.000 | 0 (0.0) | 2 (0.8) | 1.000 |
 Chronic kidney failure | 7 (2.3) | 5 (3.0) | 2 (2.0) | 0.468 | 1 (2.2) | 6 (2.3) | 1.000 | 0 (0.0) | 7 (2.7) | 0.601 |
 Heart failure | 23 (7.6) | 9 (5.4) | 14 (10.4) | 0.097 | 2 (4.3) | 21 (8.2) | 0.548 | 0 (0.0) | 23 (8.7) | 0.092 |
 Neuro disease | 8 (2.6) | 5 (5.0) | 3 (2.2) | 1.000 | 2 (4.3) | 6 (2.3) | 0.350 | 2 (5.3) | 6 (2.3) | 0.265 |
Laboratorial tests and vital signs | ||||||||||
SpO2, % | 97.0 (95.0–98.0) | 97.0 (95.0–98.0) | 97.0 (95.0–98.0) | 0.347 | 98.0 (95.0–99.0) | 97.0 (95.0–98.0) | 0.232 | 98.0 (97.0–99.0) | 97.0 (95.0–98.0) | < 0.001 |
Hemoglobin, g/dL | 13.5 (12.4–14.8) | 13.5 (12.4–14.5) | 13.4 (12.5–15.0) | 0.700 | 13.3 (12.9–14.6) | 13.6 (12.3–14.8) | 0.773 | 14.3 (13.3–15.2) | 13.4 (12.3–14.6) | 0.002 |
WBC, cell/mm3 | 7150.0 (6000.0–9000.0) | 7000.0 (6000.0–9000.0) | 7565.0 (6000.0–9150.0) | 0.755 | 8000.0 (6000.0–9912.5) | 7000.0 (6000.0–9000.0) | 0.344 | 7000.0 (6000.0–8125.0) | 7300.0 (6000.0–9000.0) | 0.506 |
Surgical characteristics | ||||||||||
Procedurea | ||||||||||
 Vascular | 2 (0.7) | 0 (0.0) | 2 (1.5) | 0.196 | 0 (0.0) | 2 (0.8) | 1.000 | 0 (0.0) | 2 (0.8) | 1.000 |
 Cardiac | 12 (4.0) | 0 (0.0) | 12 (9.0) | <  0.001 | 1 (2.2) | 11 (4.3) | 0.700 | 0 (0.0) | 12 (4.5) | 0.374 |
 Lung / Pleural | 231 (76.5) | 152 (90.5) | 79 (59.0) | <  0.001 | 34 (73.9) | 197 (77.0) | 0.654 | 27 (71.1) | 204 (77.3) | 0.397 |
 Other | 64 (21.2) | 21 (12.5) | 43 (32.1) | <  0.001 | 11 (23.9) | 53 (20.7) | 0.623 | 12 (31.6) | 52 (19.7) | 0.093 |
Condition | ||||||||||
 Elective | 283 (93.7) | 160 (95.2) | 123 (91.8) | 0.454 | 41 (91.3) | 241 (94.1) | 0.148 | 36 (94.7) | 247 (93.6) |  |
 Urgency | 13 (4.3) | 5 (3.0) | 8 (6.0) |  | 4 (8.7) | 9 (3.5) |  | 2 (5.3) | 11 (4.2) | 0.856 |
 Emergency | 6 (2.0) | 3 (1.8) | 3 (2.2) |  | 0 (0.0) | 6 (2.3) |  | 0 (0.0) | 6 (2.3) |  |
Planned duration | ||||||||||
  ≤ 2 h | 136 (45.0) | 73 (43.5) | 63 (47.0) | 0.427 | 28 (60.9) | 108 (42.2) | 0.061 | 30 (78.9) | 106 (40.2) |  |
 2–3 h | 95 (31.5) | 58 (34.5) | 37 (27.6) |  | 11 (23.9) | 84 (32.8) |  | 6 (15.8) | 89 (33.7) | <  0.001 |
  > 3 h | 71 (23.5) | 37 (22.0) | 34 (25.4) |  | 7 (15.2) | 64 (25.0) |  | 2 (5.3) | 69 (26.1) |  |
Antibiotic prophylaxis | 266 (88.1) | 146 (86.9) | 120 (89.6) | 0.480 | 38 (82.6) | 228 (89.1) | 0.213 | 27 (71.1) | 239 (90.5) | <  0.001 |
Epidural anesthesia | 72 (23.8) | 48 (28.6) | 24 (17.9) | 0.307 | 5 (10.9) | 67 (26.2) | 0.024 | 4 (10.5) | 68 (25.8) | 0.039 |
Type of tube | ||||||||||
 Endotracheal | 84 (27.8) | 11 (6.5) | 73 (54.5) | <  0.001 | 24 (52.2) | 60 (23.4) | 0.001 | 15 (39.5) | 69 (26.1) |  |
 Bronchus blocker | 19 (6.3) | 12 (7.1) | 7 (5.2) |  | 1 (2.2) | 18 (7.0) |  | 2 (5.3) | 17 (6.4) | 0.295 |
 SGA | 6 (2.0) | 2 (1.2) | 4 (3.0) |  | 0 (0.0) | 6 (2.3) |  | 1 (2.6) | 5 (1.9) |  |
 DLT | 193 (63.9) | 143 (85.1) | 50 (37.3) |  | 21 (45.7) | 172 (67.2) |  | 20 (52.6) | 173 (65.5) |  |
Duration of surgery, min | 105.0 (55.0–174.2) | 104.0 (57.5–164.8) | 105.0 (55.0–180.0) | 0.836 | 62.5 (45.0–131.2) | 110.0 (62.2–180.0) | 0.003 | 55.0 (41.2–80.0) | 115.0 (62.2–180.8) | < 0.001 |
Duration of anesthesia, min | 145.0 (90.0–225.0) | 147.5 (97.8–225.0) | 145.0 (90.0–235.0) | 0.651 | 105.0 (80.0–153.8) | 152.0 (100.0–236.0) | 0.001 | 88.0 (64.5–120.0) | 160.0 (100.0–240.0) | < 0.001 |