Lung injury induced by short-term mechanical ventilation with hyperoxia and its mitigation by deferoxamine in rats

Table 1 Arterial blood gas analysis results at 2 and 4 h (mean ± SD)

Groups	Time (h)	PaO₂ (mmHg)	PaCO₂ (mmHg)	PH	PaO₂/FiO₂ (mmHg)
MV	2	89.25 ± 3.85	34.13 ± 3.76	7.35 ± 0.05	425.00 ± 18.31
MV	4	90.25 ± 4.53	37.13 ± 3.18	7.38 ± 0.04	429.76 ± 21.56
HMV	2	204.88 ± 7.57*	33.38 ± 5.01	7.33 ± 0.05	227.64 ± 8.41*
HMV	4	208.75 ± 7.44*	36.63 ± 3.38	7.35 ± 0.03	231.94 ± 8.26*
HMV + DFO	2	205.50 ± 9.64*	36.50 ± 4.07	7.34 ± 0.04	228.33 ± 10.70*
HMV + DFO	4	208.00 ± 6.95*	37.88 ± 4.88	7.36 ± 0.04	231.11 ± 7.72*

Table 1 Data of blood gases. Values are displayed as means ± SD
Group MV Mechanical ventilation with normoxia group, Group HMV Mechanical ventilation with hyperoxia group, Group HMV + DFO Mechanical ventilation with hyperoxia+DFO group
*P = 0.000 as compared with the MV group

ISSN: 1471-2253