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Table 2 Comparisons of pre- and intraoperative findings between living donors with eGFR ≥60 mL/min/1.73 m2 and those with eGFR < 60 mL/min/1.73 m2 on POD 1

From: Delayed remnant kidney function recovery is less observed in living donors who receive an analgesic, intrathecal morphine block in laparoscopic nephrectomy for kidney transplantation: a propensity score-matched analysis

Group

eGFR ≥ 60 mL/min/1.73 m2 on POD 1

eGFR < 60 mL/min/1.73 m2 on POD 1

p

n

126

240

 

Preoperative findings

 Male sex: n (%)

39 (31.0%)

115 (47.9%)

0.002

 Age (years)

43 (29–53)

51 (42–58)

< 0.001

 Body mass index ≥25 kg/m2

34 (27.0%)

88 (36.7%)

0.062

 Hypertension n (%)

2 (1.6%)

19 (7.9%)

0.013

 Remnant kidney volume (mL)

173.0 (149.5–203.5)

170.0 (148.5–200.0)

0.717

eGFR

  ≥ 90 mL/min/1.73 m2

64 (50.8%)

133 (55.4%)

0.399

 89–60 mL/min/1.73 m2

62 (49.2%)

107 (44.6%)

 

Laboratory variables

  White blood cell count (× 109/L)

5.9 (5.0–7.0)

5.8 (5.1–6.7)

0.796

  Hemoglobin (g/dL)

13.7 (12.8–14.9)

14.1 (13.3–15.3)

0.004

  Platelet count (× 109/L)

246.5 (216.8–304.8)

243.0 (213.3–280.8)

0.115

  Glucose (mg/dL)

95 (90–101)

97 (92–103)

0.109

  Albumin (g/dL)

4.5 (4.3–4.6)

4.5 (4.3–4.6)

0.724

  Sodium (mEq/L)

141 (140–142)

142 (141–143)

0.001

  Potassium (mEq/L)

4.3 (4.1–4.4)

4.3 (4.1–4.5)

0.519

  Chloride (mEq/L)

104 (103–106)

105 (104–106)

0.125

  International normalized ratio

1.01 (0.97–1.04)

0.99 (0.96–1.03)

0.010

  aPTT (s)

27.4 (26.0–29.1)

27.1 (25.6–28.5)

0.156

Intraoperative findings

 Intrathecal morphine block

63 (50.0%)

53 (22.1%)

< 0.001

 Total surgery duration (min)

170 (155–190)

170 (147–190)

0.214

Average vital signs

  Systolic blood pressure (mmHg)

120 (112–130)

120 (115–130)

0.596

  Diastolic blood pressure (mmHg)

80 (70–80)

80 (70–80)

0.298

  Heart rate (beats/min)

76 (70–82)

72 (64–80)

< 0.001

  Body temperature (°C)

36.5 (36.3–36.8)

36.4 (36.1–36.6)

< 0.001

 Hourly fluid infusion (mL/kg/h)

4.7 (3.3–7.0)

4.4 (2.9–6.2)

0.144

 Hourly urine output (mL/kg/h)

1.0 (0.7–1.7)

0.9 (0.6–1.6)

0.084

 Total blood loss (mL)

50 (50–100)

70 (50–100)

0.353

  1. Values are expressed as medians (interquartile ranges) and numbers (percentages)
  2. Abbreviations: eGFR estimated glomerular filtration rate, aPTT activated partial thrombin time, POD postoperative day