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Table 4 Fluid requirements and per-operative haemodymics. Fluid requirements (FLUIDS); peri-operative haemodymics (HD); data as Mean ± SD - Analysis by Mann-Whitney test

From: Intravenous lidocaine to prevent endothelial dysfunction after major abdominal surgery: a randomized controlled pilot trial

 

PLACEBO GROUP

LIDOCAINE GROUP

P value for difference between groups

FLUIDS

Total in during surgery (ml)

3150 ± 1822

2410 ± 948

0.213

Fluid balance during surgery (ml)

2237 ± 1408

1758 ± 957

0.267

Total in during PACU stay (ml)

2820 ± 1208

2874 ± 1305

0.968

Fluid balance during PACU stay (ml)

1613 ± 1200

1781 ± 1204

0.598

Global fluid balance (ml)

3850 ± 1740

3540 ± 1469

0.607

HD

HR (bpm)

73.2 ± 11.6

68.7 ± 10.9

0.307

MAP (mmHg)

78.8 ± 6.8

74.9 ± 4.1

0.033

SVI (mL b−1 m−2)

39.9 ± 5.1

37.0 ± 8.8

0.088

CI (L min−1 m−2)

2.9 ± 0.6

2.4 ± 0.4

0.024

Percent of time passed with SVV < 13 (%)

66.1 ± 22.7

71.3 ± 26.0

0.335

Percent of time passed with MAP ≥70 mmHg (%)

75.7 ± 19.0

70.8 ± 15.4

0.273

Percent of time passed with CI ≥ 2.5 L min−1 m−2 (%)

68.8 ± 35.0

43.6 ± 32.9

0.025