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Table 1 Population characteristics. Placebo (PLA) group and lidocaine (LIDO) group, data as mean ± SD or n (%)

From: Intravenous lidocaine to prevent endothelial dysfunction after major abdominal surgery: a randomized controlled pilot trial

 

PLA (n = 20)

LIDO (n = 20)

Age (years)

60 ± 10.9

63 ± 12.5

Male gender

10 (50)

13 (65)

Weight (kg)

74 ± 16.5

77 ± 14.2

BMI (kg/m2)

26 ± 5.6

26 ± 4.9

ASA 1

1 (5)

1 (5)

ASA 2

15 (75)

12 (60)

ASA 3

4 (20)

7 (35)

POSSUM (physiologic)

16.9 ± 3.8

19.7 ± 4.1

POSSUM (operative)

12.4 ± 4.5

11.4 ± 2.9

POSSUM predicted morbidity (%)

32.4 ± 23.2

37.2 ± 18.6

POSSUM predicted mortality (%)

6.4 ± 9.8

6.8 ± 6.0

Cardiac Risk (LEE criteria) (%)

1.9 ± 2.4

1.4 ± 1.8

Comorbidities

 Arterial Hypertension

9 (45)

9 (45)

 Hypercholesterolemia

4 (20)

3 (15)

 Diabetis (typeI or II)

3 (15)

5 (25)

 Ischemic cardiopathy

3 (15)

2 (10)

 Other cardiopathy

0

2 (10)

 Tobacco abuse

6 (30)

6 (30)

 Renal Insufficiency (KDIGO stage <3b)

1 (5)

3 (15)

 COPD

3 (15)

3 (15)

 Stroke or TIA

1 (5)

2 (10)

 Peripheral Arterial Disease

1 (5)

0

Medications

 Beta-blockers

2 (10)

7 (35)

 Ca-channel blockers

2 (10)

0

 ACE - inhibitors

7 (35)

4 (20)

 Nitrates

0

0

 Oral Antidiabetic Agents

1 (5)

3 (15)

 Insuline

2 (10)

2 (10)

 Other Medications

17 (85)

11 (55)