Characteristic | Dexmedetomidine group | Placebo group | P value |
---|---|---|---|
(n = 80) | (n = 80) | ||
Cervical lymph node dissection, No. (%) | |||
 No | 17 (21.2) | 15 (18.8) | 0.719 |
 Unilateral | 45 (56.3) | 50 (62.5) |  |
 Bilateral | 18 (22.5) | 15 (18.7) |  |
Duration of surgery, median (IQR), mina | 330 (275, 382) | 310 (263, 393) | 0.386 |
Duration of anesthesia, median (IQR), minb | 362 (302, 428) | 358 (298, 442) | 0.732 |
Duration of limb ischemia time, median (IQR), minc | 59 (53, 71) | 60 (50, 68) | 0.611 |
Vital volume, median (IQR), ml | 425 (400, 450) | 425 (400, 450) | 0.860 |
Respiratory rate, median (IQR), breaths/ min | 12 (12, 13) | 12 (12, 14) | 0.905 |
Peak pressure, median (IQR), cmH2O | |||
 After intubation | 15 (13, 16) | 14 (13, 16) | 0.281 |
 The highest during the surgery | 16 (14, 18) | 16 (14, 18) | 0.989 |
 Before the end of the surgery | 15 (14, 17) | 15 (14, 17) | 0.664 |
FiO2, median (IQR) | 50 (50, 50) | 50 (50, 50) | 0.277 |
Intraoperative medication, median (IQR) | |||
 Sufentanil, μg | 30 (20, 40) | 30 (25, 45) | 0.083 |
 Propofol, mg | 1200 (1000, 1500) | 2500 (2000, 2700) | 0.000 |
 Remifentanil, μg | 1450 (1000, 1980) | 2625 (1700, 3000) | 0.000 |
 Dexmedetomidine, μg | 188 (168, 200) | 0 (0, 0) | 0.000 |
Crystalloids, median (IQR), ml | 1700 (1700, 2200) | 1700 (1600, 2200) | 0.947 |
Synthetic colloids, median (IQR), ml | 500 (500, 500) | 500 (500, 500) | 0.149 |
Estimated blood loss during surgery, median (IQR), ml | 300 (200, 400) | 300 (200, 350) | 0.508 |
Urine output, median (IQR) | 675 (400, 900) | 500 (350, 700) | 0.016 |
Total intraoperative infusion, median (IQR), ml | 1450 (1000, 1900) | 1450 (1075, 1875) | 0.895 |