Effect of baseline cognitive impairment on association between predicted propofol effect site concentration and Bispectral index or sedation score

Table 5 Multivariate Regression Analysis for Predictors of AvgOAA/S

Parameter	Estimate	Standard Error	t Value	P
Intercept	0.39	0.699	0.56	0.57
AvgCe	−1.55	0.137	−11.36	<.0001
AvgMAP	0.01	0.007	1.69	0.09
AvgBIS	0.04	0.006	7.15	<.0001
Age	0.02	0.021	0.83	0.41
AvgCe and Age Interaction	−0.03	0.011	−2.83	0.005
Geriatric Depression Score (GDS)	−0.02	0.021	−1.07	0.29
GDS and Age Interaction	−0.01	0.002	−2.34	0.020

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