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Table 2 Ventilator settings, blood gas analysis, and hemodynamic parameters before, 2 and 24 h after pECLA initiation

From: Validation of RESP and PRESERVE score for ARDS patients with pumpless extracorporeal lung assist (pECLA)

 Before pECLA2 h after pECLA start24 h after pECLA start
Ventilationall (n = 73)survivor (n = 37)non-survivor(n = 36)all (n = 73)survivor (n = 37)non-survivor (n = 36)all (n = 73)survivor (n = 37)non-survivor (n = 36)
peak pressure, mbar32.7+/− 6.232.6+/−7.032.6+/− 5.230.4+/− 5.4*31.4+/− 6.130.4+/− 4.5*29.4+/− 4.329.1+/− 4.429.9+/− 4.3
plateau pressure, mbar32.7+/−6.232.6+/− 7.032.6+/− 5.230.4+/− 5.4*31.4+/− 6.130.4+/− 4.5*29.4+/− 4.329.1+/− 4.429.9+/− 4.3
PEEP, mbar13.7+/− 4.113.6+/− 5.212.8+/− 4.714.4+/− 3.814.9+/− 4.213.3+/− 4.613.7+/− 3.913.7+/− 5.112.9+/− 4.7
driving pressure, mbar19.0+/− 5.618.7+/− 6.419.0+/− 4.616.2+/− 4.6*16.4+/− 5.1*16.3+/− 4.4*15.5+/− 4.215.8+/− 4.716.2+/− 4.3
TV per kg bodyweight, ml/kg4.8+/−1.64.3+/−2.04.5+/− 1.64.1+/− 1.2*3.8+/− 1.33.8+/− 0.8*4.4+/− 1.54.3+/− 1.73.7+/− 1.2
Blood gas analysis
 pH7.23+/− 0.147.24+/− 0.147.21+/− 0.157.37+/− 0.12*7.39+/− 0.12*7.35+/− 0.12*7.40+/− 0.10†7.42+/− 0.087.37+/− 0.10
 PaCO2, mmHg79.4+/−30.674.6+/− 25.785.9+/− 34.951.7+/− 11.0*49.9+/− 10.4*53.7+/− 11.5*48.6+/− 11.6†45.1+/− 11.4†‡50.9+/− 13.8†‡
 SaO2, %94.6+/−4.894.4+/− 5.794.6+/−3.695.6+/− 3.195.1+/− 6.694.9+/− 2.296.3+/− 2.4†96.6+/− 2.195.8+/− 2.7
 PaO2/FIO2, mmHg126+/− 59132 +/− 75124+/− 47107+/− 59*123+/− 73*90+/− 30*136+/− 54151+/− 49†‡120+/− 54
Hemodynamics
 heart rate, bpm103+/− 22100+/− 23104+/− 2396+/− 2195+/− 2199+/− 2292+/− 1993+/− 1991+/− 20
 MAP, mmHg76+/− 1476+/− 1177+/− 1380+/− 14*81+/− 8*80+/− 1383+/− 1383+/− 1383+/− 14
 CVP, mmHg16+/− 515+/− 416+/− 515+/− 514+/− 516+/− 614+/− 415+/− 414+/−5
 norepinephrine, μg/kg/min0.26+/− 0.350.22+/− 0.240.30+/− 0.440.28+/− 0.500.21+/− 0.230.37+/− 0.690.25+/− 0.510.17+/− 0.250.34+/− 0.69
  1. Abbreviations used for positive end expiratory pressure (PEEP), tidal volume (TV), arterial partial pressure of carbon dioxide (PaCO2), arterial oxygen saturation (SaO2), horowitz index (PaO2/FIO2), mean arterial pressure (MAP) and central venous pressure (CVP). Data presented as mean ± SD, * p < 0.05 before vs. 2 h, p < 0.05 before vs. 24 h, p < 0.05 alive vs. dead