Before pECLA | 2 h after pECLA start | 24 h after pECLA start | |||||||
---|---|---|---|---|---|---|---|---|---|
Ventilation | all (n = 73) | survivor (n = 37) | non-survivor(n = 36) | all (n = 73) | survivor (n = 37) | non-survivor (n = 36) | all (n = 73) | survivor (n = 37) | non-survivor (n = 36) |
peak pressure, mbar | 32.7+/− 6.2 | 32.6+/−7.0 | 32.6+/− 5.2 | 30.4+/− 5.4* | 31.4+/− 6.1 | 30.4+/− 4.5* | 29.4+/− 4.3† | 29.1+/− 4.4† | 29.9+/− 4.3† |
plateau pressure, mbar | 32.7+/−6.2 | 32.6+/− 7.0 | 32.6+/− 5.2 | 30.4+/− 5.4* | 31.4+/− 6.1 | 30.4+/− 4.5* | 29.4+/− 4.3† | 29.1+/− 4.4† | 29.9+/− 4.3† |
PEEP, mbar | 13.7+/− 4.1 | 13.6+/− 5.2 | 12.8+/− 4.7 | 14.4+/− 3.8 | 14.9+/− 4.2 | 13.3+/− 4.6 | 13.7+/− 3.9 | 13.7+/− 5.1 | 12.9+/− 4.7 |
driving pressure, mbar | 19.0+/− 5.6 | 18.7+/− 6.4 | 19.0+/− 4.6 | 16.2+/− 4.6* | 16.4+/− 5.1* | 16.3+/− 4.4* | 15.5+/− 4.2† | 15.8+/− 4.7† | 16.2+/− 4.3† |
TV per kg bodyweight, ml/kg | 4.8+/−1.6 | 4.3+/−2.0 | 4.5+/− 1.6 | 4.1+/− 1.2* | 3.8+/− 1.3 | 3.8+/− 0.8* | 4.4+/− 1.5 | 4.3+/− 1.7 | 3.7+/− 1.2† |
Blood gas analysis | |||||||||
pH | 7.23+/− 0.14 | 7.24+/− 0.14 | 7.21+/− 0.15 | 7.37+/− 0.12* | 7.39+/− 0.12* | 7.35+/− 0.12* | 7.40+/− 0.10† | 7.42+/− 0.08† | 7.37+/− 0.10† |
PaCO2, mmHg | 79.4+/−30.6 | 74.6+/− 25.7 | 85.9+/− 34.9 | 51.7+/− 11.0* | 49.9+/− 10.4* | 53.7+/− 11.5* | 48.6+/− 11.6† | 45.1+/− 11.4†‡ | 50.9+/− 13.8†‡ |
SaO2, % | 94.6+/−4.8 | 94.4+/− 5.7 | 94.6+/−3.6 | 95.6+/− 3.1 | 95.1+/− 6.6 | 94.9+/− 2.2 | 96.3+/− 2.4† | 96.6+/− 2.1† | 95.8+/− 2.7 |
PaO2/FIO2, mmHg | 126+/− 59 | 132 +/− 75 | 124+/− 47 | 107+/− 59* | 123+/− 73*‡ | 90+/− 30*‡ | 136+/− 54 | 151+/− 49†‡ | 120+/− 54‡ |
Hemodynamics | |||||||||
heart rate, bpm | 103+/− 22 | 100+/− 23 | 104+/− 23 | 96+/− 21 | 95+/− 21 | 99+/− 22 | 92+/− 19† | 93+/− 19 | 91+/− 20† |
MAP, mmHg | 76+/− 14 | 76+/− 11 | 77+/− 13 | 80+/− 14* | 81+/− 8* | 80+/− 13 | 83+/− 13† | 83+/− 13† | 83+/− 14† |
CVP, mmHg | 16+/− 5 | 15+/− 4 | 16+/− 5 | 15+/− 5 | 14+/− 5 | 16+/− 6 | 14+/− 4 | 15+/− 4 | 14+/−5 |
norepinephrine, μg/kg/min | 0.26+/− 0.35 | 0.22+/− 0.24 | 0.30+/− 0.44 | 0.28+/− 0.50 | 0.21+/− 0.23 | 0.37+/− 0.69 | 0.25+/− 0.51 | 0.17+/− 0.25 | 0.34+/− 0.69 |